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Targeted Muscle Reinnervation

Thought Control

  • 96 electrodes in a cylindrical grid in the socket, approx. 25 mm apart
  • measurements of signal intensity and location taken on healthy limb and applied to amputated limb
  • so the same way he would control a biological leg, he can control a bionic leg
  • gait styles (ambulation modes) each have different joint stiffness and power:
  • level ground
  • up/down ramp (10 degree slope)
  • up/down stairs w/ reciprocal gait (leg over leg)

Mechanical Stresses

Weight, Response, and other issues

  • multiple motors for articulated knee and ankle makes the leg heavy
  • less muscle to control leg + heavy leg = problems
  • 4.7 kg is weight now
  • notice the leg is very stripped down
  • all excess material has been removed
  • leg reacts/ can react faster than an actual human limb
  • misinterpretation of signals
  • difficulty getting signals: all electrodes must remain in constant, close contact with stump without becoming painful or moving very much
  • leg is noisy, and most amputees don't want huge amounts of attention on their missing limb
  • expense
  • peak torque at the ankle joint of approximately 1.6 Nm/kg in a very small amount of time (±0.2 s for a walking rate of 1 step/s)
  • average 0.35 J/kg of mechanical energy per step
  • generated power at push-off has peak of approximately 3.5 to 4.5 W/kg
  • Considering a 75 kg subject
  • max torque output approximately 120 Nm
  • power output between 250 and 350 W
  • these are average values
  • Vawter's data is protected by patient privacy
  • joints can be stiff (no elasticity), compliant (elasticity used to store energy), pneumatic (uses opposing nonlinear forces), and/or electric (a type of compliant with multiple motors)
  • physics and calculus far above my level are involved in figuring out how to make this work
  • used for upper limb amputations to control bionics
  • reattaches nerves that would go to the missing limb back to remaining muscle
  • similar procedure used in lower limb amputations to prevent nueroma formation (this is what Vawter received)
  • allows electronic signals used by nerves to be detected on the outside of the skin
  • picked up by sensors in the socket of the leg
  • interpreted by computers in the leg based on previous data
  • allows for immediate response to thought, so the fake leg reacts like a real one

Programming and Processing Data

  • pattern recognition based on other patients without TMR
  • during first gait tests, transitions between gaits were controlled remotely by researchers
  • mechanical sensors now partially control transition
  • every attempted motion has a distinct electrical signal
  • 90% accuracy with just ankle and knee flexion/extension
  • 92% accuracy also including leg rotation
  • average accuracy in non-TMR amputees: 91.0% and 86.8% respectively
  • about 40% reduction in error rate
  • ambulation error rate for only mechanical sensors: 12.9%
  • with EMG from reinnervated muscles: 1.8%
  • No buttons or hip movements to control transitions
  • many mistakes are not noticeable or not critical errors, such as mistaking an uphill ramp for stairs
  • each gait has different stiffness and torque
  • large errors common when transitioning to stair climbing drastically reduced with EMG data
  • control also possible during non-weight-bearing activity

Zac Vawter

  • lost leg above the knee in motorcycle accident in 2009
  • first user of bionic leg
  • received surgery during amputation including nerve transfers to prevent neuroma formation
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