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2012, Diabetes Care
"In this 1-year, parallel-group, randomized,open-label, treat-to-target trial, adults with type 2 diabetes with A1C of 7-10% taking OADs were randomized 3:1 to receive once daily degludec or glargine, both with metformin."
Other Basal Insulins
Is Insulin Degludec better than Insulin Glargine or other Long Acting Insulins with regard to HBa1c reduction and side effect profile?
Mean terminal half-lives are 25.4 and 12.5 h for IDeg and IGlar
47 M with poorly controlled DM2, HTN, HL here for f/u DM. DM- A1c 9.4-8.7-7.7-9.3 -->12 Today. His preprandially morning Fingersticks are typically in the 140s. Has not had any symptoms of hypoglycemia. Lowest fingerstick was 120. He states that he is compliant with his medications. Over the past year he has endorsed a weight loss of ~ 20lbs, intentionally. Despite his trending HBa1c, he states that he has been doing better with his portion control. Approached again and pt still does not want insulin. Does construction for work which is very physically taxing, but due to the cold is unable to exercise regularly. Follows yearly with an ophthalmologist, last visit was in April 2016, next is in April 2017. He now follows with a podiatrist.
Renew Januvia 100 mg tablet
Renew glyBURIDE 5 mg-metformin 500 mg tablet