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(aka Variola)
An eradicated virus that used to be contagious, disfiguring, and often deadly.
The Variola virus is a double-stranded DNA virus.
Smallpox is thought to have originated in India or Egypt at least 3,000 years ago. The earliest evidence for the disease comes from the Egyptian Pharaoh Ramses V, who died in 1157 B.C. His mummified remains show telltale pockmarks on his skin.
Humans are the only natural hosts of Variola.
There's no treatment or cure for smallpox, but there is a vaccine to prevent it. However, the vaccine's side effect risk is too high to justify routine vaccination for people at low risk of exposure to the virus.
*Smallpox is thought to have been the demise of the Aztec and Inca empires.
When smallpox was officially certified as eradicated, in December 1979, an agreement was reached under which all remaining stocks of the virus would either be destroyed or passed to one of two secure laboratories – one in the United States and one in the Russian Federation. That process was completed in the early 1980s and since then no other laboratory has officially had access to the virus which causes smallpox.