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Batrachotoxin
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Batrachotoxin
Toxicity
steroidal alkaloids extracted from the skin of the Columbian arrow poison frog
LD50 in mice is 2 μg/kg, i.v.
Highly Toxic
Believed to be made from what the frogs eat, including plants and beetles
almost extreme
Chemical Formula
Not man made
(3′,9′-epoxy-14a,18a-(epoxyethano-N-methylimino)-5β-pregna-7,16-diene-3β, 11α, 20α (2,4-dimethyl-1H-pyrrole-3-carboxylate) (Fig. 14.8)9
Smells like skunk
And is clear
C31H42N2O6
Causes numbness in human tissue, muscle and nerve depolarization, fibrillation, arrhythmias, and heart failure, as well as interfering with the body's ability to transmit electrical signals by means of action potentials. This causes death.
Batrachotoxin is used by the Embera Indians of western Colombia to poison their blow darts.
Can be detected using a modified Ehrlich reagent
Named by John Daly and Bernhard Wiktop
Batrachotoxin may one day be used as an active ingredient in pain killer ointments.
Currently, no effective antidote exists for the treatment of batrachotoxin poisoning
https://www.chemistryworld.com/podcasts/batrachotoxin/7073.article
http://www.wou.edu/las/physci/ch350/Projects_2006/Grimes/
https://www.sciencedirect.com/topics/neuroscience/batrachotoxin