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In recent decades, an average of 7 human plague cases are reported each year (range: 1-17 cases per year)
From Bubonic Plague:
Fever and chills, headache, muscle pain, general weakness, seizures
From Pnumonic Plague:
Trouble breathing, chest pain, cough, fever, headache, overall weakness, bloody sputum (saliva and mucus or pus from the lungs),
From Septicemic Plague:
Abdominal pain, diarrhea, nausea and vomiting, fever and chills, weakness, bleeding (blood may not be able to clot), shock
The Plague broke out in Europe in 1347 (started in italy from a boat coming in from Crimea) and spread. It killed 20-30 million people in Europe.
Mice, rats, ground squirrels, prairie dogs, chipmunks and rabbits, infected rat flea, and of course humans (mainly young)
Italy and spread through most of Europe
In an organism, it's found in the lymphatic system, the lungs, or the blood.
Antibiotics are the main cure for the plague
The translocation of Yernisia outer proteins that blocks the ability of the host cells to communicate with the immune system and it spreads rapidly.
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Yersinia Pestis