XYY!

Raffi Titizian

George Geregian

Shant Ganoumian

What Is XYY?

• XYY is a genetic disorder that occurs in males
• It causes them to have an extra Y chromosome
• Instead of 46 chromosomes they are born with 47

What Causes XYY?

• Most cases are due to an error during cell division in the father's sperm before reproduction occurs.
• The error occurs during anaphase II of meiosis II

XYY Syndrome!

What Is XYY?(Cont.)

• XYY syndrome is a mosaic, which means that some of the cells may have XYY chromosomes, while others may have the normal XY
• XYY occurs in about one in every 1,000 births worldwide.
• It can occur to any male an dis not limited to a certain people
• It is not an inherited disease
• Other names for XYY are Jacob's syndome, YY syndrome or 47,XYY syndome

Effects of XYY

• The effects of XYY syndrome differ from adolescnce to adulthood. Here are the symptoms for each.

Adolescence

Young/Teenage Years

These are some symptoms that babies have if diagnosed with XYY:

• Weak muscle tone
• Delayed development of walking and crawling
• Delayed or difficult speech
• Not easily excitable
• Undescended testicles

These are some symptoms of XYY that can occur during the teenage years:

• autism diagnosis
• inability to grow facial or body hair
• attention difficulties
• delayed ability to write
• delayed or difficult speech
• delayed or absent puberty
• emotional or behavioral issues
• enlarged breast tissue
• muscle spasms
• low testosterone levels
• weak muscle tone
• learning disabilities
• small penis
• undersized testicles
• taller than average height
• weak bones

Adulthood

These are some symptoms that adults have if diagnosed with XYY:

• decreased sex drive
• decreased sperm counts
• infertility

What Did We Learn?

Is XYY Inherited?

• While finding research for our project, we learned a lot about this disorder and what its about.
• WHen we first started doing research, we thought that this disorder doesnt really affect its victim, but after digging deeper, we came to a conclusion that it has many different symptoms that can affect the daily lives of people carrying it.

• XYY syndrome is not inherited.
• It is a random event that occurs during cell division
• It is neither dominant nor recessive
• A person who has XYY cannot pass on the syndrome to his son.

Treatment

• XYY cannot be cured
• Some therapies to reduce the symptoms are testosterone replacement therapy, fertility therapy, speech therapy, physical therapy, and educational therapy
• Testosterone replacement therapy helps teenage boys go through puberty,and helps older men improve their sex drive
• Fertility treatment can improve the chances for the person to have a child.

Diagnosis

• XXY may be undiscovered until a male reaches adulthood, unless you go to regular checkups
• Two tests can be used to diagnose XYY syndrome:
• Hormone testing
• Chromosome analysis