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Rudolf virchow

Camillo golgi

Kölliker

Peter Behrens

Flemming

1858 – Rudolf Virchow (physician, pathologist and anthropologist) expounds his famous conclusion: omnis cellula e cellula, that is cells develop only from existing cells.

1857 – Kolliker described mitochondria.

1879 – Flemming described chromosome behavior during mitosis.

1883 – Germ cells are haploid, chromosome theory of heredity.

1898 – Golgi described the golgi apparatus.

1938 – Behrens used differential centrifugation to separate nuclei from cytoplasm.

This thing is the last model of the cell membrane.The fluid-mosaic model describes the plasma membrane of animal cells.The plasma membrane that surrounds these cells has two layers of phospholipids (fats), which at body temperature are like vegetable fluid.The membrane look like a mosaic shape because this is made up of many different parts and they include macromolecules.

Historical Development Of The Cell

Merve Parlak 118 9/B

Fluid Mosaic Model

1981 – Transgenic mice and fruit flies are produced. Mouse embryonic stem cell line established.

1995 – Tsien identifies mutant of GFP with enhanced spectral properties

1998 – Mice are cloned from somatic cells.

1999 – Hamilton and Baulcombe discover siRNA as part of post-transcriptional gene silencing (PTGS) in plants

1939 – Siemens produced the first commercial transmission electron microscope.

1952 – Gey and coworkers established a continuous human cell line.

1955 – Eagle systematically defined the nutritional needs of animal cells in culture.

1957 – Meselson, Stahl and Vinograd developed density gradient centrifugation in cesium chloride solutions for separating nucleic acids.

1965 – Ham introduced a defined serum-free medium. Cambridge Instruments produced the first commercial scanning electron microscope.

1976 – Sato and colleagues publish papers showing that different cell lines require different mixtures of hormones and growth factors in serum-free media.

Timeline

1595 – Jansen credited with first compound microscope

1655 – Hooke described 'cells' in cork.

1674 – Leeuwenhoek discovered protozoa.

1833 – Brown described the cell nucleus in cells of the orchid.

1838 – Schleiden and Schwann proposed cell theory.

1840 – Albrecht von Roelliker realized that sperm cells and egg cells are also cells.

1856 – N. Pringsheim observed how a sperm cell penetrated an egg cell.

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