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Probability of

Polydactyly

Polyfdactyly

  • One in every five hundred humans are born with extra digits
  • .4% of humans have it and 99.6% do not

Whi?

  • Hardy and Weinberg set out to fail at disproving evolution
  • Concocted conditions that would eliminate evolution

[It didn't work]

Haw?

Fun

Finger Facts

  • Only works if five conditions are met
  • Mathematical Equation:
  • p+q=1 [phenotype]
  • p(p)+2pq+q(q)=1 [genotype]
  • Use the frequencies of the alleles in place of 'p'&'q'
  • p(p)=homozygous dominate, pq=heterozygous, q(q)=homozygous recessive
  • Polydactyly follows an autosomal dominant pattern of inheritance. Its is not sex linked, and the parent’s offspring have a 50% chance of inheriting the disease
  • 8 infants were born alive with polydactyly in the UK 2002 (University of Ulster, 2003)
  • 0 fetal deaths or stillbirths occurred due to polydactyly in the UK 2002
  • 3 cases of induced abortions occurred following prenatal diagnosis of polydactyly in the UK 2002 (University of Ulster, 2003)
  • Polydactyly occurred in 3.74 per 10,000 births in the UK 2002

Double Dose of Digit

Digression

  • 4 infants were born alive with syndactyly in the UK 2002
  • 0 fetal deaths or stillbirths occurred due to syndactyly in the UK 2002
  • 3 cases of induced abortions occurred following prenatal diagnosis of syndactyly in the UK 2002
  • Syndactyly occurred in 2.38 per 10,000 births in the UK 2002

Hardy-Weinberg

Equilibrium

The Proportion

Changed

Works Cited

Wut?

  • nfstc.org. (n.d.). Retrieved from http://www.nfstc.org/pdi/Subject07/pdi_s07_m01_02.htm
  • (2011). Westlake high school. (2011). [0]. Retrieved from http://www.conejo.k12.ca.us/whs/Departments/Science.aspx
  • English!nfo. Retrieved from http://english.turkcebilgi.com/Smoking+pipe+(tobacco)
  • Evi. (n.d.). Retrieved from http://www.evi.com/q/facts_about__wilhelm_weinberg
  • Right diagnosis. (23 A). Retrieved from http://www.rightdiagnosis.com/p/polydactyly/stats.htm
  • Arnold, P. (2009, 09 29). Bright hub. Retrieved from http://www.brighthub.com/science/genetics/articles/47390.aspx
  • Combination of biology and statistics
  • Deals with population genetics and gene frequencies in populations
  • Must have five conditions met
  • large population
  • random breeding
  • isolation of populations
  • no/limited mutations
  • No natural selection

Polydactyly

The Six Fingered Fumble

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