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Phencyclidine (PCP)

Pharmacodynamics

PCP Facts

Pharmacokinetics

-Other common names: angel dust, stardust, and peace pill

-PCP is a hallucinogen

-Original purpose: anesthetic pharmaceutical use

Routes of Administration:

-PCP generally comes in powder or pill form

-Most common method of administration is smoking

-Main molecular target for PCP are NMDA receptors

-two binding sites: 1) magnesium

2) PCP

Biobehavioral Effects

Physical Dependence

Behavioral Effects

Behavioral Tolerance

Long Term Effects:

-Impaired memory

-Impaired thinking and decision making

-Aphasia

-Hallucinations and delusions

-Severe depression suicidal thoughts

Short Term Effects:

Low Dosage

-Numbness, relaxation

-Invincibility

-Sense of well-being and euphoria

-Problems concentrating

-Slurred speech

-Irritability

Higher Dosage

-Delusions

-High blood pressure and heart rate

-Anxiety and panic

-Respiratory depression

PCP and Positive Reinforcement

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