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In Vivo vs In Vitro

Introduction

In vivo

Index

What is in vivo ?

  • Within the living
  • Animals
  • In vivo
  • in vitro

  • Primary cells
  • Cell lines
  • Tissue

  • Disadvantages
  • Advantages

In Vitro

What is In vitro ?

  • In glass
  • Cells

References

  • Jan van der valk, In vitro-methoden: Een natuurlijk alternatief voor dierproeven? Universiteit Utrecht. Biotechniek december 2012
  • In vivo

https://en.wikipedia.org/wiki/In_vivo

  • In vitro

https://en.wikipedia.org/wiki/In_vitro

  • In vitro and skin testing for allergies

http://www.ncbi.nlm.nih.gov/pubmed/3050840

http://www.europemc.org/abstract/med/10181996

SDEH - H09PDT - HC 18

HLO - B&M

Hogeschool leiden

17-9-2015

Maarten Morsink

Gabrielle Pinkse

In Vitro

Disadvantage

Extrapolating results to the biology of the intact organism

Advantages

Nikita Korpel s1084478

Esmay van der Toorn s1081016

Chantal Vaarting s1082546

Focusing on a small number of components

Human cells can be used directly

In Vitro

Tissue

  • Disadvantage
  • Skin
  • Advantage

Cell lines

  • Immortalized cells
  • HeLa cell line
  • Advantage
  • Disadvantage

Primary cells

  • Advantage
  • Disadvantage
  • Nerve tissue
  • Skin cells
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