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Aldosterone
Disorders Associated with Aldosterone
How is it regulated?
-Hyperaldosteronism can be caused by a tumor in the adrenal gland or may be a response to some diseases.
-Addison's disease is caused by damage to the adrenal glands, which make hormones to control the body’s response to stress, and balance body salt and water.
-Negative feedback regulation
-Aldosterone is responsible for regulating sodium homeostasis, thereby helping to control blood volume and blood pressure.
-Aldosterone targets epithelial cells in the kidney.
Aldosterone plays a central role in the regulation of blood pressure mainly by acting on organs such as the kidney and the colon to increase the amount of salt (sodium) reabsorbed into the bloodstream and the amount of another salt called potassium removed in the urine
-Made by the adrenal glands.
-Secreted from the kidneys in response to variations in blood pressure and volume and plasma sodium and potassium levels.
Abbreviation: ALDO