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Types of Gallstones
imbalance between cholesterol and bile salts. Bile salts normally emulsify choelsterol BUT when cholesterol is too high, CAN'T BREAK 'EM DOWN! thus Bile becomes supersaturated with cholesterol -- forming crystals
Associated with obesity, Crohn disease, cystic fibrosis, advanced age, clofibrate, estrogen therapy, multiparity, rapid weight loss
Types of Gallstones
Cholesterol Stones
3 types
Pigment stones are more common in cirrhosis or sickle cell anemia.
pigment stones 5-10%
cholesterol stones 10%
mixed 75-90%
Pigment Stones
infection inc pigment stone formation
complex mixture of abnormal insoluble Ca2+ salts of UNCONJUGATED bilirubin and inorganic Ca salts
Ju Eun Lee
formed in gallbladder
migrate to cystic duct, common bile duct, ampulla
Mixed Stones
20-80% cholesterol
Yellowish shiny faceted stones, Thick inflammed gallbladder