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1767: Daniel Boone explores Kentucky for the first time.
1836: Battle of the Alamo - Mexican troops attack the Alamo Mission killing all but two Texans. This spurs the Texans on in the Texas Revolution.
1805: Lewis and Clark reach the Pacific Ocean - Explorers Lewis and Clark map out areas of the Louisiana Purchase and eventually reach the Pacific Ocean.
1841: Oregon Trail - People begin to travel west in wagon trains on the Oregon Trail. Around 300,000 people would take the trail over the next 20 years.
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1845: Manifest Destiny - Journalist John O'Sullivan first uses the term "Manifest Destiny" to describe the westward expansion of the United States.
1838: Trail of Tears - The Cherokee Nation is forced to march from the east coast to Oklahoma. Many thousands die along the way.
1830: Indian Removal Act - Congress passes a law to move Native Americans from the Southeast to the west of the Mississippi River.
1803: Louisiana Purchase - President Thomas Jefferson buys the Louisiana Territory from France for $15 million. This doubles the size of the United States and provides a large area to the west of the country for expansion.