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Proteus Syndrome
PROTEUS SYNDROME
Named after Greek sea god, Proteus, who would change his shape to keep from getting caught
first identified by Michael Cohen Jr. in 1979
named by German pediatrician, Rudolf Weidemann in 1983
known to carry a germline mutation of
the tumour suppressor gene PTEN, on chromosome ten
works cited
PTEN. (August 2007) Genetics Home Referance retreived December 13, 2010 http://ghr.nlm.nih.gov/gene/PTEN
Elephantiasis. Health Grades. Retreived December 13, 2010
http://www.wrongdiagnosis.com/e/elephantiasis/intro.htm.
Proteus System. last reveiw unknown. University of Kansas Medical Center. Retreived December 13,2010.
http://www.kumc.edu/gec/support/protwww.html.
Symptoms
blood clots lodgred in lungs that could prove fatal
overgrowth of multiple tissues, and bones
increased size of organs
tumors
Deep lines and overgrowth of soft tissue on the soles of the feet
raised, rough skin
People with Proteus Syndrome
There are very few people with Proteus syndrome, the most famous is Joseph Merrick also known as, The Elephant Man
Facts
There is no cure for proteus syndrome, they can do surgery to get rid of harmful tumors but they raise the risk of death with every surgery performed
life expectancy varies with the severity of the case
Affects more males than females
can affect any race or nationality
often mistaken for elaphantiasis
Elephantiasis: Lymphatic obstruction which causes severe swelling in the legs and groin area. It is usually caused by infection with a parasitic worm which is transmitted by mosquito bites.