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Syphilis

Stage 2

What is it?

  • The pathogen spreads through the blood to the skin, liver, joints, lymph nodes, muscles, and brain.
  • A rash frequently appears about 6 weeks to 3 months after the chancre has healed.
  • At this time, the disease is highly infectious, because bacteria are present in the secretions from the lesions.
  • A chronic bacterial disease that is contracted by infection during sexual intercourse, but also congenitally by infection of a developing fetus
  • Syphilis is spread through vaginal, oral, and anal sex during the infection's primary, secondary, and early latent stages.

Stage 1

Stage 3

Treatment

  • Appears 2 to 10 weeks following exposure.
  • A red, oval sore, called a chancre develops at the site where the bacteria entered the body.
  • Most chancres appear on the penis, anus, and rectum in men, and on the vulva, cervix, and between the vagina and anus (perineum) in women.
  • Penicillin is the standard treatment for primary, secondary, and early latent syphilis.
  • For those allergic to penicillin, antibiotics tetracycline, doxycycline, minocycline, erythromycin, and ceftriaxone may be used, though less effective
  • Begins 3 or more years after infection
  • The person may no longer be contagious, but the bacteria may multiply and spread throughout the body, damaging the heart, eyes, brain, nervous system, bones, and joints
  • Tumors may develop
  • Degenerative central nervous system disease can produce dementia and damage is irreversible.

Diagnosis

  • Diagnosed when the chancre on the genitals is observed and by reviewing the patient's sexual history
  • Blood, serum, and plasma tests
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