The pathogen spreads through the blood to the skin, liver, joints, lymph nodes, muscles, and brain.
A rash frequently appears about 6 weeks to 3 months after the chancre has healed.
At this time, the disease is highly infectious, because bacteria are present in the secretions from the lesions.
A chronic bacterial disease that is contracted by infection during sexual intercourse, but also congenitally by infection of a developing fetus
Syphilis is spread through vaginal, oral, and anal sex during the infection's primary, secondary, and early latent stages.
Stage 1
Stage 3
Treatment
Appears 2 to 10 weeks following exposure.
A red, oval sore, called a chancre develops at the site where the bacteria entered the body.
Most chancres appear on the penis, anus, and rectum in men, and on the vulva, cervix, and between the vagina and anus (perineum) in women.
Penicillin is the standard treatment for primary, secondary, and early latent syphilis.
For those allergic to penicillin, antibiotics tetracycline, doxycycline, minocycline, erythromycin, and ceftriaxone may be used, though less effective
Begins 3 or more years after infection
The person may no longer be contagious, but the bacteria may multiply and spread throughout the body, damaging the heart, eyes, brain, nervous system, bones, and joints
Tumors may develop
Degenerative central nervous system disease can produce dementia and damage is irreversible.
Diagnosis
Diagnosed when the chancre on the genitals is observed and by reviewing the patient's sexual history