Osteogenesis Imperfecta

Osteogenesis Imperfecta

By: Taylor Miller

How is OI prevented?

Type III

Work Cited

Symptoms

Blue sclera

What is it?

Bastos, F. B., Perez, L. T., Narváes, C. P. D. L., Costa, O., Souto da Silva, R. C., Dias Van-

Dunem, J. C. V., . . . de Menezes, A. (2010). Severe osteogenesis imperfecta: case report.

einstein, 8(4). Retrieved from http://apps.einstein.br/revista/arquivos/PDF/1863-

Einsteinv8n4_pg480-482_eng.pdf

Hattersley, L. (2014, March 1). Brittle Bone Disease - Osteogenesis Imperfecta [Video file].

Retrieved from

Osteogenesis imperfecta. (2007). In World of Health. Gale. Retrieved from http://

ic.galegroup.com/ic/scic/ReferenceDetailsPage/ReferenceDetailsWindow?

failOverType=&query=&prodId=SCIC&windowstate=normal&contentModules=&display

-

query=&mode=view&displayGroupName=Reference&limiter=&currPage=&disableHighli

ghting=false&displayGroups=&sortBy=&search_within_results=&p=SCIC&action=e&cat

Id=&activityType=&scanId=&documentId=GALE

%7CCV2191500940&source=Bookmark&u=nysl_ce_moboces&jsid=303512e3aa7ea709638

98464ae126fb4

Rauch, F., & Glorieux, F. H. (2004). Osteogenesis imperfecta. The Lancet, 363(9418),

1377-85. Retrieved from http://search.proquest.com/docview/199122725?accountid=37208

Rehrmann, A. (2007, January 5). For girl, 3, every move poses risk of injury. New York

Times, p. B5(L). Retrieved from http://ic.galegroup.com/ic/scic/NewsDetailsPage/

NewsDetailsWindow?

failOverType=&query=&prodId=SCIC&windowstate=normal&contentModules=&display

-query=&mode=view&displayGroupName=News&limiter=&currPage=&disableHighlighti

ng=false&displayGroups=&sortBy=&search_within_results=&p=SCIC&action=e&catId

• Low set ears

• Curved spine

• Hearing loss

• Thin skin

• Unusual amount of broken bones

• May have over 100 fractures before adolescents

• Shorter than normal height

• Most severe in children who survive the neonatal period

• Spend most of the day laying down

• There is no way to prevent it

• People who have OI should know the risks of passing the gene onto children

• This disease is a genetic disorder that affects one of the two genes that codes for the chain of collagen one

https://ucfbelovedproject.wordpress.com/2012/04/23/the-broken-family-disease-o-i/

http://www.healthandfitnesstalk.com/tag/oi/

Is there a cure?

Type II

Atticus Shaffer

How is OI diagnosed?

The 4 main types

Type IV

It affects how strong the bone is.

• There is no cure

• There are ways to ease the symptoms

What causes it?

• Slightly shorter than normal

• Can be diagnosed in utero

• After the child is born
• DNA tests

• Most severe

• Causes death shortly after birth

• abnormally formed rib cage

• Types I, II, III, IV

• The least severe types are types I, IV, and V, followed by types VI, VII, and III. Type II is the most severe

Which include...

Thank You

• Swimming

• Physical therapy

• Splints and casts

• Metal rods

Spontaneous mutation in the collagen gene

In the case of 3 year old, Shenay, who has type III

she has speech, feeding and occupational therapy twice a week. Also she gets calcium injections every 3 months.

• Plays Brick Heck on the TV show The Middle
• Has type IV OI
• At the prefect height to play a younger character

http://www.oif.org/site/PageServer?pagename=OIF_PrivacyPolicy

Some stats

This is what the inside of a bone should look like

Type I

• There are also types V to VIII. Some specialists think that type VII should not be included.

• 20,000 to 50,000 in the United Sates have OI
• It affects the same number of males and females

• The patient might experience 20-40 fractures before adolescents

• May be slightly shorter then but very close to normal height

• Triangular face

• Type VII has only been detected in native Americans in Northern Quebec