SKIN DONATION

SKIN DONATION

SKIN GRAFT AND ITS BENEFITS

NEED FOR SKIN DONATION

*Acts as the most effective dressing for

the burned patients.

* Acts as a barrier to infection & the rate

of infection is reduced significantly.

* Reduces the pain of the burned patients.

* Lessens the hospital stay of the burned patients.

* Increases the survival rate of the burned patients.

* Decreases the Cost of treatment.

* It is an ideal and cost-effective dressing compared to highly expensive artificial

skin substitute.

SKIN GRAFTS - ORIGINAL BASED

INTRODUCTION

a)Autograft: The donor skin is taken from

a different site on the same individual's

body (also known as an autologous).

b)Isograft or syngraft: The donor and

recipient individuals are genetically identical (e.g., monozygotic twins, animals of a single inbred strain; Isogeneic).

c)Allograft: The donor and recipient are of the same species (humanhuman, dogdog; allogeneic).

d)Xenograft or Heterograft: The donor and recipient are of different species (e.g.,

bovine cartilage; xenogeneic).

Burn wound is probably the most devastating

of all the wounds – physically, psychologically, socially and economically. In case of extensive burns, the protective barrier, the skin, is burnt and the body is thrown wide open to entry of infectious agents. If we do not cover the burnt area immediately with some skin substitutes, then patients die of infection. It is said that

skin is the best substitute for another skin.

It is also the cheapest substitute compared

to artificial skin substitutes.

SKIN BANK

EQIPMENTS

* Bio-Safety cabinet (is an enclosed,

ventilated laboratory workspace)

* Mesher (A Tissue Expansion System

manufactured by Zeemech Instruments.)

* Centrifuge (is used to separate small

amounts of suspension)

* Sealer ( is a machine used to seal products)

* In shaking incubator (applications

include cell culturing, cell aeration,

and solubility studies)

* Fridge (used to store the removed skin)

* The estimated annual burn incidence in India

is approximately 6-7 million per year, majority of the extensively burnt patients die.

* Nearly 1 to 1.5 lakh people get crippled and require multiple surgeries and prolonged rehabilitation.

* WHO 2008 report says adequate burn care is currently beyond the reach of the vast majority of the world’s poor. This leads to high mortality in cases with a moderate level per cent body burn.

* In Mumbai alone, about 1000 burn patients

need donor skin annually. One burn

patient requires skin from two

donors.