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Congenital Insensitivity to Pain

By: Migueline Louis Jeune

Congenital Insensitivity to pain

websites:

http://science.howstuffworks.com/life/inside-the-mind/human-brain/cipa.htm

https://www.hinsdale86.org/staff/kgabric/Disease10/Congenital%20Insensitivity%20to%20Pain%20with%20Anhidrosis/

Age it affects

The girl who annot feel pain.

Prognosis and Diagnosis

The most common age it affects is birth because people are usually born with it. Some people live till adulthood but other died while still young.

Most people who are diagnosed with this disease die before the age three. but if they live longer they will be in a wheelchair.

  • Fever and burns
  • Infection
  • Injuries
  • Genetic testing

Preventions

There are no specific ways of stopping or preventing the disorder, but the way doctors treat it is by focusing on preventing:

Congenital insensitivity to pain Anhidrosis (CIPA) is a disease where a person cannot feel any pain. It's a rare disease in the US. Also it's in inherited disease from family members through genes. People who are diagnose by it have difficulty eating well because it caused food to be tasteless because of biting on the tongue. It can also affect urinate because you don't feel the need to use the bathroom.

  • injuries
  • infection

Signs and Symptoms

Risk Factors

The only risk factor is a family history. If your recessives had it long time ago it might come again in the future by skipping generations .

  • Lack of pain and temperature sensations
  • High fevers
  • Unintentional injuries
  • Biting of the tongue, lips and burning fingers

What causes it?

In other words it means both copies of the gene in each cell have mutations. Also the parents have an autosomal recessive trait and each of them have one copy of the mutated gene.

The reason why this disorder happens is because of the mutations in the NTRK1. The NTRK1 is a receptor located on the surface of cells and there are neurons that transmit pain temperature and touch sensation.

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