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Todd's Syndrome

A neurological condition that distorts human perception

Janelle Agustin

Physiology

October 2, 2015

Vision Distortion

Size Distortion

Teleopsia

Pelopsia

Micropsia

Macropsia

Objects appear much further than they actually are

Objects appear much closer than they actually are

Objects appear smaller than they actually are

Objects appear larger than normal

Answer

Which of the following in not an example of distorted perception?

References

a. Macropsia

b. Micropsia

c. Peleopsia

d. Teleopsia

  • Evans R MD. Reversible Palinopsia and the Alice in Wonderland Syndrome Associated with Topiramate Use in Migraineurs. Headache. 2006;815-818.
  • Hamed S. A migraine variant with abdominal colic and Alice in wonderland syndrome: a case report and review. BMC Neurology. 2012;10:1-5.
  • Uca A, Kozak H. The Wonderland Syndrome: A case of Aura Accompanying a Cluster Headache. Balkan Medical Journal. 2015;32:320-2.
  • http://well.blogs.nytimes.com/2014/06/23/alice-in-wonderland-syndrome/
  • http://lenus.ie/hse/bitstream/10147/128190/1/Article6086.pdf

e. None of the above

Aspiration: Pharmacy

Requirements

Background

Alice in Wonderland Syndrome

1. Cumulative & Science GPA: 2.50-3.0

2. Courses in Physiology with lab, Anatomy with lab, Cell Biology with lab, Microbiology with lab, General Biology with lab, General and Organic Chemistry with lab, Public Speaking, Economics, English Composition

3. Three letters of recommendation

Science professor, Pharmacist,

Person of choice

  • UCI Class of 2015
  • BS Public Health Sciences
  • Pharmacy Volunteer
  • CHOC volunteer
  • OC Global Medical Center Volunteer
  • Neuromuscular Researcher
  • Student Involvement

Question

PharmCAS

Which of the following in not an example of distorted perception?

a. Macropsia

b. Micropsia

c. Peleopsia

d. Teleopsia

e. None of the above

History

  • British Psychiatrist, Dr. John Todd, coined "Todd's Syndrome" in 1955
  • Patients with severe migraines experienced skewed perceptions
  • No patients had a mental illness or brain tumors

Alice in Wonderland

Scientific Method

A migraine variant with abdominal colic and Alice in wonderland syndrome

Current Cases

  • Published in 1865
  • Lewis Carroll had migraine problems
  • Speculated using his own experiences to write this story

Observation: Subjects experienced distorted human perceptions

Hypothesis: These distorted perceptions are characterized by or results from severe migraines

Testable prediction: Use of nuclear medicine techniques to detect abnormal cerebral areas

Experiment/Observation: Changes in cerebral areas went back to normal once the "episode" disappeared

Treatment

Currently, there is no effective treatment

Most people "grow" out of it in their teen years

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