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The bacili are inhaled into the alveoli of the lungs where they take up residence in the Macrophages and begin to multiply.
Differentiated from other non-tuberculous Mycobacterium
Treatment is based on three principles:
Eliminates TB that are slow metabolizers
Sterilizes sputum of TB not removed by INH
1. Kaiser, G. E. The Prokaryotic Cell: Bacteria – The Cell Wall, [homepage on the internet]. C2011 [updated 2011 April; cited 2012 March 20.] http://faculty.ccbcmd.edu/courses/bio141/lecguide/unit1/prostruct/afcw.html
2. Knechel, N. CE Article: Tuberculosis: Pathophysiology, Clinical Features, and DiagnosisCrit Care Nurse. April 2009 29:34-43; doi:10.4037/ccn2009968
3. Toriyama S, Yano I, Masui M, Kusunose E, Kusunose M, Akimori N. Regulation of cell wall mycolic acid biosynthesis in acid-fast bacteria: I. Temperature-Induced changes in mycolic acid molecular species and related compounds in Mycobacterium phlei J Biochem (1980) 88(1): 211-221
4. Nair A. The times of India. Animals big source of TB infection: expert [homepage on the internet]. c2011 [updated 2011 Dec 27; cited 2012 Mar 12]. Available from: http://articles.timesofindia.indiatimes.com/2011-12-27/nagpur/30561236_1_tb-patients-animals-disease
5. Tuberculosis: Learn the signs and symptoms of TB disease [homepage on the internet]. c2010 [updated 2010 Jul 14; cited 2012 Mar 10]. Available from: http://www.cdc.gov/Features/TBsymptoms/
6. Tuberculosis [homepage on the internet]. c2012 [updated 2012 Mar; cited 2012 Mar 5]. Available from: http://www.who.int/mediacentre/factsheets/fs104/en/
7. Mahon C, Lehman D, Manuselis G. Textbook of diagnostic microbiology. 4th ed. W. B. Saunders Company; 2011.
8. Martinko J. Brock biology of microorganisms. 11th ed. Pearson Prentice Hall; 2006.
9. Center for Disease Control. Module 3: Diagnostic laboratory methods for tuberculosis. Atlanta. Available from: wwwn.cdc.gov/dls/ILA/.../Kenya1103/Ch2/Module3methods.rtf.
10. Ogbaini-Emovon E. Current trends in the laboratory diagnosis of tuberculosis. Benin J. Postgrad. Med.[serial of internet]. 2009 Dec;11:79-90.
11. Duerden BI. Standards of laboratory diagnosis of tuberculosis [unpublished lecture notes] Department of Health. Available from: https://s3-eu-west-1.amazonaws.com/bsmt/asm21/Brian_Duerden.ppt.
12. American Thoracic Society. Treatment of tuberculosis and tuberculosis infection in adults and children. American Journal of Respiratory Care and Critical Medicine. 1994; 149: 1359-1374.
13. Center for Disease Control and Prevention: Treatment for TB Disease [homepage on the Internet]. 2011 [updated 2011 December 9; cited 2012 March 19]. Available from: http://www.cdc.gov/tb/topic/treatment/tbdisease.htm.
14. Janin YL. Antituberculosis Drugs: Ten years of research. Bioorganic and Medicinal Chemistry. 2007; 15: 2479-2513.
15. Gillespie SH. Evolution of Drug Resistance in Mycobacterium tuberculosis: Clinical and Molecular Perspective. Antimicrobial Agents and Chemotherapy. 2002; 46(2): 267-274.
16. Kalinda AS, Aldrich CC. Pyrazinamide: A Frontline Drug Used for Tuberculosis. Molecular Mechanism of Action Resolved After 50 Years? ChemMedChem. 2012; 7(3).
17. Center for Disease Control and Prevention: Drug-Resistant TB [homepage on the Internet]. 2011 [updated 2012 January 17; cited 2012 March 19]. Available from: http://www.cdc.gov/tb/topic/drtb/default.htm.
18. Udwadia ZF, Amale RA, Ajbani KK, Rodrigues C. Totally Drug-Resistant Tuberculosis in India. Clinical Infectious Diseases. 2011; 54(4): 579-581.
19. Nature: Totally Drug-Resistant TB Emerges in India [homepage on the Internet]. 2012 [updated 2012 January 13; cited 2012 March 20]. Available from: http://www.nature.com/news/totally-drug-resistant-tb-emerges-in-india-1.9797
Therapeutic Agent:
Time Course:
Therapeutic Agent:
Time Course:
http://pathmicro.med.sc.edu/infectious%20disease/mycobacterial%20diseases.htm
http://www.finddiagnostics.org/programs/tb/find_activities/led_microscopy.html
Agarwal et al. Annals of Clinical Microbiology and Antimicrobials 2005 4:18 doi:10.1186/1476-0711-4-18
http://textbookofbacteriology.net/tuberculosis.html - Kenneth Todar PhD
http://www.icrc.org/eng/resources/documents/photo-gallery/tuberculosis-photos-2011-03-17.htm
http://www.google.ca/imgres?q=TB+resistant+strains&um=1&hl=en&sa=N&rlz=1R2ADFA_enCA455&biw=1215&bih=730&tbm=isch&tbnid=ea5WDD5BuFCosM:&imgrefurl=http://www.maltastar.com/dart/20120319-malta-among-countries-with-low-tb&docid=RWEdC8hocebg5M&imgurl=http://www.maltastar.com/userfiles/tn/t_460x0_tuberculosis.jpg&w=460&h=272&ei=vZ13T_LzE62-0QHcgaWlDQ&zoom=1&iact=hc&vpx=567&vpy=86&dur=32&hovh=173&hovw=292&tx=184&ty=117&sig=107943214122160261010&page=4&tbnh=127&tbnw=214&start=68&ndsp=20&ved=1t:429,r:7,s:68
M. Tuberculosis is spread from one person to another via respiratory aerosols. These are produced whenever we...
http://homepage.usask.ca/~trn186/pth205/path.html
http://www.hss.gov.yk.ca/tb.php