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Eppley, Aalst, Robey, Havlik, Sadove (2003)
Unilateral CL-CP
Bilateral CL-CP
Median Cleft Lip
Discern subtle relationships between genetics-environment and orafacial clefts
Lateral Facial Clefts
Median Mandibular Cleft
Oblique Facial Clefts
Unilateral and bilateral CL-CP
Two Models:
Van der Meulen: Nasomaxillary dysplasia
Tessier's Classification: Tessier no. 1
Two Genetic Variabilities:
1. Syndromic
Ex: Van der Woude Syndrome
2. Nonsyndromic
Genetic Factors:
Cleft Lip Cause:
Failure of medial nasal process and lateral nasal and maxillary processes to either contact or maintain contact
Cleft Palate Cause:
Secondary palate fails to fuse completely