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Kim Austin
Lone Star College Montgomery Honors
Most infections target skin or soft tissue
Skin Abscess
Scalded Skin Syndrome
CDC: General Information about MRSA in Healthcare Settings.
Mrsasurvivors.org
Carbuncle
Impetigo
Photos: Staph infection Resources.org
Endocarditis
Image from CDC.org
Baron, S. (1996). Medical Microbiology 4th Edition. Galveston: University of Texas Medical Branch at Galveston.
Basic Local Alignment Search Tool. (n.d.). Retrieved March 20, 2015, from http://blast.ncbi.nlm.nih.gov/Blast.cgi?PROGRAM=blastn&BLAST_PROGRAMS=megaBlast&PAGE_TYPE=BlastSearch&SHOW_DEFAULTS=on&LINK_LOC=blasthome
CDC. (2013, September 16). General Information about MRSA in Healthcare Settings. Retrieved November 15, 2014, from CDC.gov: http://www.cdc.gov/mrsa/healthcare/index.html
Dealing with MRSA or Staph Infection Issues? (n.d.). Retrieved March 24, 2015, from http://www.staph-infection-resources.com/
National Center for Biotechnology Information. (n.d.). Retrieved September 14, 2014.
NIH News. (1999, May 27). Experimental Staph Vaccine Broadly Protective in Animal Studies. Retrieved November 10, 2014, from National Institute of Allergy and Infectious Diseases: http://web.archive.org/web/20070505050641/http://www3.niaid.nih.gov/news/newsreleases/1999/staph.htm
Col (Group A) Compared to MRSA (Group E)
Takuno et al. (2012). Population Genomics in Bacteria: A Case Study of Staphylococcus aureus
(n.d.). Retrieved March 13, 2015, from http://phil.cdc.gov/PHIL_Images/02122002/00007/PHIL_851_lores.jpg
Stoppler, M. C. (2014, July 11). Staph Infection (Staphylococcus aureus). Retrieved November 20, 2014, from Medicinenet.com: http://www.medicinenet.com/staph_infection/article.htm
Takuno analyzed genome-wide pattern of single
nucleotide polymorphisms (SNPS) to classify 12
strains of s. aureus into 5 groups: A, B, C, D, & E.
Takuno et al. (2012). Population Genomics in Bacteria: A Case Study of Staphylococcus aureus. Retrieved September 12, 2014.
Todar, K. P. (2012). Staphylococcus. Retrieved November 12, 2014, from Textbookofbacteriology.net: http://textbookofbacteriology.net/staph.html
The purpose of this project was to test
this classification system by using a
whole genome analysis.
What is a Microbe? (n.d.). Retrieved March 30, 2015, from http://archives.microbeworld.org/microbes/
MRSA (Group E) compared to each of the 12 analyzed strains
Photoshop and GIMP were used to create a composite image by layering each dot-plot on one another
Professor Ricky Johnson
Dr. Julie Harless
Lone Star Montgomery Honors College
Classification systems used the rRNA in the
bacteria's ribosome as the changes were
infrequent and relatively easy to track.
Ribosomes are the sites at which information carried in the genetic code is converted into
protein molecules.
Mannitol Salts Agar:
Both S. Aureus and S. Epidermidis
can survive on the high-salt content
plate, but only S. Aureus can ferment
mannitol visible by the yellow color
change on the plate.
Mannitol Salts Agar
Coagulase Test:
S. aureus is coagulase positive. Coagulase allows the bacteria to isolate itself from the host's defenses by converting fibrinogen to fibrin to form a blood clot.
Credit: Major differences.com
Coagulase Test
S. Aureus is a facultative anerobe,
and can survive both with and
without oxygen.
Aerobic respiration
Gram stain from microbeworld.net