Chromosomes become visible, the nucleolus disappears, the mi

Chromosomes become visible, the nucleolus disappears, the mitotic spindle forms, and the nuclear envelope disappears. Chromosomes become more coiled. Each duplicated chromosome is seen as a pair of sister chromatids joined by the duplicated but unseparated centromere.

G1 is when the cell makes more ribosomes and proteins, so that it can grow to its proper size. S phase is when it copies its DNA, the proteins that package DNA, and more cell membrane material. G2 phase is when the organelles divide, and the last phase before mitosis begins.

The chromosomes move to opposite ends of the poles and begin to unwind. A nuclear envelope forms around each set of chromosomes, the nucleoli reform and ribosomes are assembled. As the nucleoli forms, the cell's cytoplasm begins to divide.

the second stage of mitosis. During prometaphase, phosphorylation of nuclear lamins by M-CDK causes the nuclear membrane to break down into numerous small vesicles. As a result, the spindle microtubules now have direct access to the genetic material of the cell.

The chromosomes become arranged on the metaphase plate and are attached to the now fully formed spindle. The centrosomes are at opposite poles of the cell. The chromosomes, now at their most highly coiled and condensed, become arranged on a plane equidistant from the two poles called the metaphase plate.

The spindle fibers continue to shorten and move towards opposite ends or poles of the cell. This causes the cell to elongate. The chromosomes during anaphase usually have a distinct V shape.