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Malaria is a disease transmitted by mosquito that affects humans and other animals.
The disease is most commonly spread by an infected female Anopheles mosquito.
parasites that cause malaria is belong to the genus Plasmodium
is a genus of mosquito first described and named by J. W. Meigen in 1818.
About 460 species are recognised; while over 100 can transmit human malaria, only 30–40 commonly transmit parasites of the genus Plasmodium,
Like all mosquitoes, anophelines go through four stages in their life cycles: egg, larva, pupa, and imago.
Anopheles life stages
There are several species (kinds) of Plasmodium that cause malaria in humans:
which causes serious disease
which causes milder disease
causes milder disease
causes milder disease
species which normally infect other primates
Generally the presentation may include:
- headache
- fever
- shivering
- joint pain
- vomiting
- anemia
- jaundice
- hemoglobin in the urine
- eye damage
- convulsions
The classic symptom of malaria is paroxysm—a cyclical occurrence of sudden coldness followed by shivering and then fever and sweating, occurring :
diagnosis of malaria in non-endemic areas requires a high degree of suspicion, which might be elicited by any of the following: recent travel history, enlarged spleen, fever, low number of platelets in the blood, and higher-than-normal levels of bilirubin in the blood combined with a normal level of white blood cells
Malaria is usually confirmed by the microscopic examination of blood films or by antigen-based rapid diagnostic tests (RDT)
Microscopy is the most commonly used method to detect the malarial parasite—about 165 million blood films were examined for malaria in 2010
Although polymerase chain reaction-based tests have been developed, they are not widely used in areas where malaria is common as of 2012, due to their complexity
There is no vaccine for malaria
Methods used to prevent malaria include medications, mosquito elimination and the prevention of bites
The presence of malaria in an area requires a combination of high human population density, high anopheles mosquito population density and high rates of transmission from humans to mosquitoes and from mosquitoes to humans.
Vector control refers to methods used to decrease malaria by reducing the levels of transmission by mosquitoes. For individual protection, the most effective insect repellents are based on DEET or picaridin.[62] Insecticide-treated mosquito nets (ITNs) and indoor residual spraying (IRS) have been shown highly effective in preventing malaria among children in areas where malaria is common
Malaria is treated with antimalarial medications; the ones used depends on the type and severity of the disease. While medications against fever are commonly used, their effects on outcomes are not clear.
Simple or uncomplicated malaria may be treated with oral medications. The most effective treatment for P. falciparum infection is the use of artemisinins in combination with other antimalarials (known as artemisinin-combination therapy, or ACT), which decreases resistance to any single drug component