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Human Recombination
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Genetic recombination in Humans
What is genetic recombination ?
Genetic recombination in Humans
Genetic recombination can be of the following types:
- Homologous recombination
- Nonhomologous recombination
- Site-specific recombination
- Mitotic recombination
Recombination Enzymes
- E. coli
- RecA
- ligase
- DNA polymerase
- Saccharomyces cerevisiae.
- Tumor suppressor gene { BRCA1 and BRCA2}
Genetic Recombination Appears to be Common in the Human Genome
Research paper
Advances in genetic sequencing and analysis techniques have revealed the many changes that can happen in the human genome throughout a lifetime. Now reporting in Cell, researchers have also found that certain repetitive parts of the genome can also recombine far more often than we knew. Once disregarded as 'junk' DNA, long, repetitive stretches of the genome seem to undergo many recombination events, which we are only now starting to decipher.
Introduction
Somatic cell genetics, means genetic studies of cells other than germ cells, but it is usually used more restrictively, referring to mammalian cells in tissue culture.
Somatic cell Genetics
Hybridomas
- Hybridoma is a culture of hybrid cells that results from the fusion of B cells and myeloma cells.