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You are MO2 Oncall and ED rang you to refer a 44Y homeless man for:-
i) hyperglycemia (Dstix 20.3, urine glucose +++ ketone –ve)
ii) AKI 2” dehydration (Cr 124 baseline 64, Na 126, K 3.3)
ED senior remarked that he is escorted by police for disrupting the peace by damaging public property. Not much is known about the patient except his forensic records revealed that he underwent:-
- community service for juvenile theft in his mid teens
- troubled past with polysubstance use
- convicted of assault and imprisoned from 2007-2013
- voluntarily admitted under Pusat Al-Islah from 2013-2015
No records exist from 2015 onwards.
However police interviewed some eyewitnesses familiar with him who often spotted him working in the nasi katok stall at Serusop for the past 7 years. He would sleep below the stairs on the shoplots in the night. Sometimes he would be spotted screaming and kicking door entrances. His employer could not be reached at present.
Once arriving at trolley area, ED senior exercised caution as he sedated pt with IM midazolam 5mg 40 min ago due to aggressive behaviour.
Upon entering Room 2, you find 2 police officers and the patient on the stretcher with one arm and foot handcuffed to the frame. He is semi-conscious, barely opening eyes to voice and mumbling. You ask him for his name but he is neither oriented in time, place or person.
You attempt to get some collateral from police officers however they know little and are only present until pt is admitted to the ward. As you proceed to perform physical exam on the pt, he starts to exhibit signs of aggression by unshackling himself from the handcuffs while grunting.
A: Give oral sedation e.g. PO lorazepam 2mg STAT
B: Give IM sedation e.g. IM haloperidol 5mg STAT
C: Instruct police officers to remove handcuffs
D: Correct hyperglycemia (basal-bolus insulin) and electrolyte derangement (IV fluids)
E: Verbal de-escalation and ensure safe surroundings
After successfully persuading the patient to take oral sedation, you perform a quick neurological exam before he dozes off. Able to follow most instructions and neurologically intact except for reduced sensation & proprioception all limbs. You noticed bruises and superficial ulceration on his MCP joints as well as an infected Rt toe with poorly healed foot ulcers. Apart from reduced JVP and dry mucous membranes, rest of examination is unremarkable and you note your findings.
During PTWR, you present your case to the medical consultant oncall and treating the patient as hyperglycemia not in crisis on BG of poorly-controlled T2DM, AKI 2” dehydration and infected diabetic foot ulcers. Your consultant agrees with your assessment and decides for admission under AMU with Psych & Ortho input. In addition, your consultant asked the following:-
A: Schizophrenia
B: Bipolar affective disorder, manic episode
C: Metabolic disorder
D: Neurological disorder
E: Substance use disorder
The patient is then stabilised at AMU for the next three days however he appears to communicate with one or his favourite two word sentences “inda tau”. At times, he would not respond and mutters as his eye contact wanders around. In the meantime, Psychiatry hasn’t had any luck contacting the employer (notes mentioned that the nasi katok stall doesn’t have a valid permit) and MSW is in touch with JAPEM for any relative contact details or patient’s files. Ortho has ordered a pus swab CS, performed debridement of infected toe and started IV co-amoxiclav.
On D4 admission, AMU nurse contacts you to say that patient is pyrexial at 40.2degC, agitated and screaming “gangguan” (disturbances). On bedside review, pt is pointing towards the IV drip and repeated the words “gangguan” with the nurse preventing him from pulling out his drip. You address his name but he only looks at you briefly before becoming fixated with the IV drip.
A: Address cognitive impairment and/or disorientation
B: Address potential sources of infection
C: Address disturbed behaviour with sedation
D: Address pain
E: Promote good sleep patterns
Neurological disorders
Drugs
Systemic disorders
You move patient to one of the AMU rooms and initiate delirium management protocol.
You identify the source of the infection to come from the Rt foot however there appear to be multiple small abscesses below the knee.
You captured an image and WhatsApped to your SMO who recommended escalating Abx to IV meropenem, repeat set of investigations including FBC, CRP, UEC, LFT, blood CS & CXR.
Patient’s condition deteriorated slightly on the next 30-minute review and following discussion with your senior you are asked to refer to ICU for supportive therapy and notify the ID team.
Within an hour later, lab phoned the nursing staff informing that the pus swab grew Burkholderia pseudomanii.
You have since rotated into ID and have taken up the case of the homeless man now lodged in ICU for meiloidosis with multi organ involvement. Although pt did not require intubation, he required plenty of supportive therapy and deconditioned throughout his long stay in ICU. He was stepped down after 1 month and placed in the general ward where he underwent rehab by OT/PT. Initially he communicates in short sentences, tolerates oral feeds and participates in rehab.
Gradually over the next few weeks nursing staff & OT/PT reports that pt is becoming increasingly withdrawn, eventually refusing to partake in rehab, reduced oral intake to 2-3 tablespoons, insomnia and was heard remarking “baiktah ku mati”
Based on your assessment, what severity of depression does this pt have?
Core: low mood, anergia, anhedonia
Mild: 2 core + 2 sx
Mod: 2 core + 3-4 sx
Severe: 3 core + >5sx
S leep changes
I nterest loss
G uilt
E nergy loss
C oncentration loss
A ppetite changes
P sychomotor changes
S uicidality/self harm
Duration: >2 weeks
You inform your consultant during the next WR who agreed with your assessment and started on antidepressant fluoxetine 20mg OD. In the following week, he started to complain of abdo cramps, nausea and loose stools. Gradually he started to participate in rehab and regained some of his appetite back. However the OT/PT remarked that pt has been rather flirtatious and talkative towards them in addition to being easily distracted which hinders rehab. He is also mildly irritable when asked to take his oral medications and disturbs other patients in the night. Despite that, nursing staff are able to manage him albeit barely.
A: Switch to another antidepressant
B: Stop antidepressant
C: Add mood stabilizer
D: Add antipsychotic
E: Add antispasmodic
D istractibility
I ndiscretion
G randiosity
F light of ideas
A ctivity increase
S leep decrease
T alkativeness
At least 1 manic/hypomanic episode + 1 depressive episode
Duration: Hypomanic >4d Manic >1wk
Based on your assessment, is this BPAD I or BPAD II?