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HEMOPHILIA

Definition

Hemophilia is a rare disorder in which the blood doesn't clot in the typical way because it doesn't have enough blood-clotting proteins (clotting factors).

Definition

Types

1. Congenital hemophilia: hemophilia is usually inherited, meaning a person is born with the disorder (congenital).

There are three types of hemophilia:

  • Hemophilia A: This is the most common type of hemophilia. It happens when you don’t have enough clotting factor 8 (factor VIII).
  • Hemophilia B: Hemophilia B happens when you don’t have enough clotting factor 9 (factor IX.)
  • Hemophilia C: Hemophilia C is also known as factor 11 (factor XI) deficiency. This hemophilia type is very rare.

2. Acquired hemophilia is a variety of the condition that occurs when a person's immune system attacks clotting factor 8 or 9 in the blood. It can be associated with:

  • Pregnancy
  • Autoimmune conditions
  • Cancer
  • Multiple sclerosis
  • Drug reactions

3. Hemophilia inheritance

Types

Symptoms

The most significant symptom is unusual or excessive bleeding or bruising.

How much bruising or bleeding people have depends on whether they have severe, moderate or mild hemophilia:

  • People with severe hemophilia often have spontaneous bleeding or bleeding for no apparent reason (ex sudden bloody noses)
  • People with moderate hemophilia who have serious injuries may bleed for an unusually long time ( ex after surgery, after dental treatment or a cut finger)
  • People with mild hemophilia may have unusual bleeding, but only after major surgery or injury.

Other symptoms may include:

  • Joint pain from internal bleeding. Joints in your ankles, knees, hips and shoulders may ache, swell or feel hot to the touch.
  • Bleeding into your brain. People with severe hemophilia very rarely develop life-threatening bleeding into their brains. Brain bleeds may cause persistent headaches, double vision or make you feel very sleepy.

Symptoms

In babies and children

1.Sometimes, babies assigned male at birth with hemophilia are diagnosed because they bleed more than usual after being circumcised.

2. Other times, children develop symptoms a few months after they’re born. Common symptoms include:

  • Bleeding
  • Swollen lumps on their heads
  • Fussiness, irritability or refusal to crawl or walk
  • Hematomas

In babies and children

Treatment

The best way to treat hemophilia is to replace the missing blood clotting factor so that the blood can clot properly. This is done by infusing (administering through a vein) commercially prepared factor concentrates. People with hemophilia can learn how to perform these infusions themselves so that they can stop bleeding episodes and, by performing the infusions on a regular basis (called prophylaxis), can even prevent most bleeding episodes.

Treatment

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