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In a patient with heart failure, what is the response of the parasympathetic and sympathetic nervous system?
In a patient with heart failure, what is the response of Pans and Sans?
By: Mikael Habtezion, Andrew Hean, Gabby Mackey, Stephanie Phung, Emily Woo
What is heart failure?
According to the American Heart Association, "heart failure is a chronic, progressive condition in which the heart muscle is unable to pump enough blood to meet the body’s needs for blood and oxygen. "
According to the CDC, "about 5.7 million adults in the United States have heart failure."
Who does heart failure affect?
What is the body's response?
Goal: Increase Heart Rate and Increase Blood Flow
Alpha 1, Alpha 2, Beta 1, Beta 2
(Adrenergic)
SANS
Flight/Fight
M1, M2, M3
(Muscarinic)
PANS
Rest/Digest
SANS/PANS Receptors
Heart
Receptors
Work to increase heart rate and blood flow
Heart
Heart
Beta 1/Beta 2 activation increases heart rate and increases strength of contraction
M2 inhibition prevents the heart rate from decreasing
Vessels
Vessels
Alpha 1 activation increase venous tone and increase arterial resistance
Kidneys
Beta 1 activation increase reabsorption