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Transcript

Safe Handling of Chemo Drugs

By: Jennifer Liu

INTRO

Intro

  • Chemotherapeutic agents are a risk to HCP's due to its inherent toxicity and the extent to which the workers are exposed to the drug
  • Primary routes of exposure: direct skin contact and inhalation of aerosolized drug products
  • Risks include of exposure: increased risk of cancer, organ damage, teterogen
  • Although risk cannot be completely eliminated, a variety of things can be done to reduce risk

Safe Handling

Safe Handling

  • Transfer chemotherapy tablets/ powder into syringe barrel without touching them (wear PPE)

  • Open capsules in a biohazard hood

  • Dissolve tablets in water rather than crush them

  • Prepare each dose on an absorbant pad on an uncluttered surface

  • Discard materials that have been in contact with tablets/ capsules (medicine cups, oral syringes) as hazardous waste

  • Wash hands after preparing medication

PPE

PPE

  • Gloves
  • Tested to protect against chemotherapy agents are recommended
  • Minimum acceptable standard is powder free latex surgical gloves (0.007 inches)
  • Should be changed after each administration OR if contamination or puncture occurs OR every 60 min

  • Gown
  • Must be worn whenever chemotherapy agents are being manipulated or administered
  • Disposable, impermeable/ low permeability fabric, lint free, with back closure and long cuffed sleeves (should be tucked into gloves)
  • Mask
  • Designed to protect against aerosolized products N95 or N100 recommended

  • Plastic Face Shield
  • Must be worn whenever chemotherapy agents are being manipulated or administered
  • Safety glasses or regular eye glasses are not adequate

*Must be worn when handling any patient's blood or body fluids*

Transport

Transport

  • cytotoxic drugs must be placed in a closed, leak-proof bag

  • transport from the pharmacy must be done in a rigid, shock-resistant, leak-proof container that can can be easily cleaned and decontaminated

  • the bottom must be covered in an absorbant pad

  • mechanical transport systems such as pneumatic tubes must not be used
  • stress on content
  • whole transport system would be compromised if a leak occured

  • transport container must be labeled with the "Cytotoxic" hazard symbol

Safe Administration

  • PPE must be worn
  • Up to 48 hours post administration of IV chemo agents
  • Up to 7 days post administration of oral chemo agents

  • Plastic absorbant pads should be placed under tubing and syringes

  • Only syringes and tubing with Luer-Lok connections should be used

  • Infusion bags should be changed at waist level

Safe Administration

Safe Disposal

Safe Disposal

  • All syringes and needles should be discarded in containers that are puncture-resistent, leak proof, that have lids that seals securely, and are labeled with the biohazard symbol

  • Bags and solution administration sets should be discarded intact in labeled resealable containers that are puncture-proof and leak-proof

  • PPE used during handling and administration should be disposed of in a biohazard labeled container

  • Recommend all toilets to be flushed twice

  • Briefs should be disposed in a biohazard container up to 7 days of chemo administration

  • Contaminated, non-disposable linen should be handled with PPE and disposed following the agency's policy of handling and disposal of infectious linens

  • Biohazard containers should be a different colour from regular waste/ sharps containters
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