What is the Krebs Cycle?
1
Who discovered the Krebs Cycle?
6
The Krebs Cycle is a series of chemical reactions that occur in the mitochondria of cells to oxidize acetyl-CoA and produce ATP, NADH, and FADH2.
When does Krebs Cycle occur?
The Krebs Cycle is named after Sir Hans Adolf Krebs, a German-British biochemist who discovered its steps and mechanisms.
2
It takes place during the middle stage of cellular respiration, following glycolysis after the pyruvate is converted into acetyl CoA, whenever the cell needs energy.
Krebs Cycle
The Krebs Cycle, also known as Citric Acid Cycle , is an important step in cellular respiration that occurs in the mitochondria of eukaryotic cells. It plays a central role in the generation of ATP (adenosine triphosphate), which is the primary energy source of cells.
How does the Krebs Cycle work?
3
Where does the Krebs Cycle occur?
5
- The cycle starts with the condensation of acetyl-CoA and oxaloacetate, forming citrate.
- Through a series of enzyme-catalyzed reactions, citrate is broken down, releasing carbon dioxide and transferring electrons to carrier molecules NADH and FADH2.
- These electron carriers then participate in the electron transport chain to generate ATP.
4
Why is the Krebs Cycle important?
The Krebs Cycle place within the mitochondria, which is often referred to as the "powerhouse" of the cell due to its role in energy production.
- Energy Extraction:Krebs Cycle extracts energy from fuel molecules, releasing electrons.
- ATP Production: It uses these electrons to generate ATP, the cell's primary energy currency.