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BIOLOGICAL BASIS OF BEHAVIOR

Chapter 2

How much of our behavior is based on our brain?

The brain houses a complex web or nuerons, synapses, neurotransmitters, & electrical impulses

So what if something happens to our brain?

NERVES

IT'S JUST NERVES

PHINEAS GAGE

Gage is a railroad worker/foreman

Explosives used to blast paths open

Tamping iron used to push explosives down into holes

CHANGES TO THE BRAIN

Rod propells through Gage's head

Gage miraculously lives - gets up to go right back to work

2 months later, returns to the job... but there's something different

Gage's personality becomes more hostile, animalistic, shrewd, and erratic

Damage to his brain left certain functions untouched, others changed

NEURONS

Glial cells - garbage trucks of the nervous system

Insulate neurons as well - myelin

Cells of the nervous system that conduct impulses

They take information like light or temperature and pass that info to the brain

It is in the brain that most of our neurons exist

NERVOUS SYSTEM

Neurons vary on location and function

Most have body, axon, and dendrites

Nucleus is the power source of the neuron

Dendrites receive the message

Axon sends the message along

Messages and Myelin

Messages and Myelin

Axon carries the impulse to the axon terminals

The "end of the line" occurs at other neurons, muscles or glands

These networks become more complex as an individual matures

Myelin insulates the axon providing a smooth neural impulse

Infants develop myelin as they grow

MS patients lose this protective sheathing

Afferent and Efferent Neurons

Afferent and Efferent Neurons

How do you know it hurts when you stub your toe? Afferent neurons (or sensory neurons) carry that message to your spinal cord and brain

Before you can yell (or maybe curse) your efferent (or motor) neurons tell you to pick up your foot and perform a one-legged dance while holding your toe

Your pulse may increase or you may start sweating

It's just + & -

  • Neural impulses - messages that travel within neurons
  • Ions within and outside the neuron - at rest negatively charged chloride inside
  • Stimulus depolarizes the neuron - if not enough stimulus => nothing happens
  • If enough stimulus - action potential reached => message sent

THE CONNECTION

The Firing Neuron

Threshold needs to be met in order for the neuron to fire

When the neuron fires the strength of the impulse is constant

This is known as the all-or-none principle

REFRACTORY

REFRACTORY

A time period after the neuron fires when it connot send messages from a stimulus

Only a few thousandths of a second

Space between and axon terminal and the nearest dendrite - synaptic cleft

Not like the arcing of an electrical spark

Neurotransmitter chemicals are released from the axon terminal

These specific neurotransmitters are designed to fit intricately into receptors

This "lock and key" mechanism ensures that the correct neurotransmitter is correctly accepted by the dendrite

The Synapse

Neurotransmitters

Chemical keys to communication

Each fits the receptor site intended

Any neurotransmitter left behind will be reabsorbed by the axon terminal - reuptake

CHEMICAL KEYS

Acetylcholine (ACh)

Can be excitatory and inhibitory

Curare: poison that stops ACh from assisting muscle movement

Dopamine - neurotransmitter involved in pleasure perception, voluntary movement, learning and memory

Drugs like alcohol and nicotine highten levels of dopamine

Decreased levels of dopamine - Parkinson's (loss of muscle control) jerky, uncoordinated movement

Schizophrenia also linked to dopamine - patients have too many receptors - hallucinations through overutilization (too much stimulus)

ACh typically found in the hippocampus

This brain structure is, in part, responsible for memory storage

Alzheimer's sufferers have decreased levels of ACh available to the brain

An experiment decreased the amount of ACh in lab rats; could not remember how to navigate a maze they'd run before

GABA - gamma-aminobutyric acid: an inhibitor

Could be involved in anxiety reduction - combined with alcohol GABA effects can be amplified - loss of inhibition/anxiety

Endorphins - another inhibitor - explains how an athlete can continue with an activity while incurring an injury

These are naturally produced in the brain and prevent pain causing chemicals from reaching their receptors

Morphine is a synthetic endorphine - same "pain dulling" effects

The Take-home...

Neurotransmitters are the microscopic reasons we do what we do, think, feel, etc.

In total, these elements form the basis of everything that occurs within us

But how does all this occur within our body?

Norepinephrine - an excitatory neurotransmitter involved in general arousal, learning and memory, and eating

Can also be a hormone

Artificial stimulants can mimic norepinephrine (cocaine and speed) - can both facilitate the release and block the reuptake

Repeated use can lead to dependency

Serotonin - emotional arousal and sleep

A powerful neurotransmitter; deficiencies can lead to alcoholism, depression and aggression

CHEMICAL KEYS

THE NERVOUS SYSTEM

THE NERVOUS SYSTEM

Central and peripheral

The central nervous system consists of the brain and spinal cord

Where most of the processing happens

The peripheral nervous system "makes the rest work" - these are the outer components (like the mouse, keyboard, moniter)

How do you smile or simply stand up straight?

A combination of both the central and peripheral nervous systems

You scared the Bejesus outta me!!!

AHHH!!!

Think of a time when you were very frightened. List the bodily symptoms you experienced.

Think of a time when you were very calm and relaxed. What sorts of bodily symptoms did you experience then?

THE PARTS...

Parts of the nervous systems

Somatic and Autonomic nervous systems

  • Somatic - afferent and efferent neurons
  • Transmits sensory messages
  • Autonomic - also afferent and efferent but controls glands and internal organ muscles
  • Automatic responses - heartbeat, breathing, digestion
  • Two divisions - sympathetic and parasympathetic

Sympathetic and Parasympathetic

Sympathetic - excites the organs and nervous system - "fight or flight"

Parasympathetic - calming process to bring the body back to homeostasis

Central Nervous System

Spinal cord - bundle of nerves transmitting messages to the brain

Spinal reflex - unlearned response that happens before the message makes it to the brain

Gray matter - old brain matter

White matter - myelinated sections (association areas)

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