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Addison's Disease

Carolyn Murphy

General Psychology

Cortisol

The hormone involved in Addison's disease is cortisol. Cortisol Is produced in the adrenal glands. The targeted organs and structures for cortisol are the liver, muscles, adipose tissue and the pancreas.

Topic 1

Regulation

The secretion of cortisol is regulated by hypothalamus hormone (CRH) and the pituitary hormone (ATCH) located in the hypothalamus-pituitary-adrenal axis.

Subtopic 1

Functions

Cortisol controls blood sugar levels, regulates metabolism, helps to reduce inflammation, and assists with memory formulation

Title

Homeostasis

Cortisol is involved in various maintenance such as blood pressure, the immune system, anti-inflammatory actions and the metabolism of proteins, carbohydrates and adipose.

Topic 2

Hyper-secretion vs. Hypo-secretion

Addison's disease is the hypo-secretion of cortisol and mineralocorticoids, meaning the body does not produce enough of them.

Topic 3

Symptoms

Hypo-secretion can cause weakness, fatigue, and low blood pressure. When Addison's disease is left untreated of you have a damaged adrenal gland symptoms can include sudden dizziness, vomiting and even loss of consciousness.

Subtopic 3

Treatments

Hormone replacement therapy is used to correct levels of steroid hormones that aren't being produced. Oral medications include: Hydrocotisone (Cortef), predinsone or methylprednisolone to replace cortisol.

Topic 4

Perspective

Addison's Disease Psychological Affects

Addison's disease has been linked to cause emotional and behavioral changes. This disorder has been associated with irritability, depression and poor concentration.

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