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30 yrs female 20 weeks pregnant complains of RUQ abdominal pain every 3-4 days
- pain Occurs after fatty meals
- US showed : multiple stones, no wall thickening
- blood labs: Normal LFTs, amylase, lipase
Dx: Cholelithiasis
Questions?
Should I offer her a cholecystectomy?
Timing of surgery?
Open or laparoscopic?
- If laparoscopic ?
- what pre-operative care should be done ?
- What entry technique should be used?
- Port placement?
- Appropriate level of pneumoperitoneum?
- Patient positioning?
- 1 in 500 women will require non-obstetrical abdominal surgery during pregnancy .
- The most common surgical emergencies complicating
pregnancy are acute appendicitis and cholecystitis.
- Previously: laparoscopy was contraindicated during
pregnancy due to concerns for uterine injury from trocar placement and fetal malperfusion due to pneumoperitoneum.
NOW
- As surgeons gained more experience and documented their
outcomes, laparoscopy has become the preferred treatment modality for many surgical diseases in the pregnancy.
Diagnosis
Patient selection
Traditionally, the recommendation for non-emergent procedures during pregnancy has been to avoid surgery during the first and third trimesters to minimize the risk of
spontaneous abortion and preterm labor, respectively.
- Recent literature has demonstrated that pregnant patients may undergo laparoscopic surgery safely during any trimester without an increased risk to the mother or fetus .
Both laparoscopic cholecystectomy and appendectomy have been successfull
performed late in the third trimester without increasing the risk of preterm labor or fetal demise .
SO...
Laparoscopy can be safely performed during any trimester of pregnancy when operation is indicated .
Fetal Heart Monitoring:
----------------------------------
- Fetal heart monitoring of a fetus considered viable should be done
preoperatively and postoperatively in urgent abdominal surgery .
Tocolytics:
---------------
- Tocolytics should not be used prophylactically in pregnant women
undergoing surgery but should be considered perioperatively when signs of preterm labor are present.
Surgery guidlines
Beyond the first trimester should be placed in
the left lateral decubitus position or partial left lateral decubitus position
minimize compression of the vena cava
to
- In first trimester the initial access to abdomen can be done through umbilical accroding the fundus level.
- In second and third trimester:
- left subcostal approach is recommended as initial access to the abdomen to avoid the uterus injury.
- CO2 insufflation of 10-15 mmHg can be safely used for
laparoscopy in the pregnant patient.
-The level of insufflation pressure should be adjusted to the patient’s physiology
- Intraoperative and postoperative pneumatic compression devices and early postoperative ambulation are recommended prophylaxis
for deep venous thrombosis in the gravid patient.
- In patients who require anticoagulation during pregnancy, unfractionated heparin has proven
safe and is the agent of choice.
- Is the treatment of choice for pregnant patients with acute appendicitis.
- CO2 insufflation of 10-15 mmHg by Veress needle at Palmer's point.
- Port placement.
- Is the treatment of choice in the
pregnant patient with symptomatic gallbladder disease, regardless of
trimester.
- Pregnant women with acute cholecystitis should undergo cholecystectomy.
- A study reports when cholecystitis is
managed by surgery incidence of fatal mortality is only 2.6%. However, on conservative management it is 8.0%.
Ramin KD, Ramsey PS. Disease of the gallbladder and pancreas in
pregnancy. Obstet Gynecol Clin North Am 2001;28:571-80.
- Cox TC, Huntington CR, Blair LJ, Prasad T, Lincourt AE, Augenstein VA, Heniford
BT (2016) Laparoscopic appendectomy and cholecystectomy versus open: a study
in 1999 pregnant patients. Surg Endosc 30:593-602
- Cheng HT, Wang YC, Lo HC, Su LT, Soh KS, Tzeng CW, Wu SC, Sung FC, Hsieh
CH (2015) Laparoscopic appendectomy versus open appendectomy in pregnancy:
a population-based analysis of maternal outcome. Surg Endosc 29:1394-1399
- Reedy MB, Galan HL, Richards WE, Preece CK, Wetter PA, Kuehl TJ (1997)
Laparoscopy during pregnancy. A survey of laparoendoscopic surgeons. J Reprod
Med 42:33-38
- Arvidsson D, Gerdin E (1991) Laparoscopic cholecystectomy during pregnancy.
Surg Laparosc Endosc 1:193-194
- Glasgow RE, Visser BC, Harris HW, Patti MG, Kilpatrick SJ, Mulvihill SJ (1998)
Changing management of gallstone disease during pregnancy. Surg Endosc
12:241-246
91. Affleck DG, Handrahan DL, Egger MJ, Price RR (1999) The laparoscopic
management of appendicitis and cholelithiasis during pregnancy. Am J Surg
178:523-529
- Korndorffer JR Jr FE, Reed W (2010) SAGES guideline for laparoscopic
appendectomy. Surg Endosc 24:757-761
152. Cox TC, Huntington CR, Blair LJ, Prasad T, Lincourt AE, Augenstein VA, Heniford
BT (2015) Laparoscopic appendectomy and cholecystectomy versus open: a study
in 1999 pregnant patients. Surg Endosc
153. Schwartzberg BS, Conyers JA, Moore JA (1997) First trimester of pregnancy
laparoscopic procedures. Surg Endosc 11:1216-1217
154. Thomas SJ, Brisson P (1998) Laparoscopic appendectomy and cholecystectomy
during pregnancy: six case reports. JSLS 2:41-46
155. Barnes SL, Shane MD, Schoemann MB, Bernard AC, Boulanger BR (2004)
Laparoscopic appendectomy after 30 weeks pregnancy: report of two cases and
description of technique. Am Surg 70:733-736