Introducing
Your new presentation assistant.
Refine, enhance, and tailor your content, source relevant images, and edit visuals quicker than ever before.
Trending searches
He Jiankui's Lulu and Nana experiment of 2018 was the first of its kind: a genetic modification of human genomes that resulted in a pregnancy. Jiankui took the embryo from parents with HIV+ genes, modified the receptive gene, and the parents produced a child (twins) codenamed "Lulu and Nana"
Human Genome Editing: Our Future Belongs to All of Us -Baylis
Anthony Wallace / AFP - Getty Images
Based on the description CRISPR Therapeutics provided, CRISPR "edits genes by precisely cutting DNA and then letting DNA repair processes take over"
Cas9 is an enzyme that binds to a specific DNA segment, unwinds the strand segment and attaches a guide RNA to the unwound double strand. If the RNA and DNA are bound perfectly, Cas9 causes a double bond breakage and the DNA repair mechanisms repair the DNA
Disruptions, deletions, insertions
Crisprtx.com/gene-editing/crispr-cas9
Arvin Gouw
Human Genome Editing: Our Future Belongs to All of Us -Baylis
There are global laws against pregnancies involving modified embryos.
While there have been multiple experiments involving changing the genes of embryos (germline editing) and changing the genes of fully-grown adults (gene therapy/somatic editing), changing the genomes of an embryo that results in a pregnancy is illegal based on bioethics.
Mayo Clinic
Proposed resolution by 116th Congress in July 2019
RCSB.org
Research has been completed and shown that CCR5 modification by CRISPR has shown readiness in off-target gene mutations.
Thomas J. Cradick et. al
Research has been done on animals to reconfigure genomes for beneficial purposes
Researchers in Yunnan, China edited specific genes in the embryos of macques, codenamed "Mingming" and "Lingling", and placed them in a surrogate mother to test the difficulty of the process.
This is the first of such experiments to ever take place (2013).
Genome Editing - Christina Larson
Genome Editing - Christina Larson
Steve Dorus, PhD, Syracuse University
"There will always be people that will take either side of the coin: those that will responsibly use the technology for the bettement of others and those that will use it for the advancement of offspring" -Steve Dorus, PhD
Germline enhancement has the capability of changing features that can give social and socio-economic advances.
National Academies Press
Memegenerator.com
National Academies Press
We go through massive changes to our bodies through replacement surgeries, such as cataract surgery and hip replacements, by using foreign objects that assist in structural support.
This is the same concept as genomic modification: technology and foreign objects are coming in to replace and/or upgrade dysfunctional body parts
Rory J. Ferguson et. al.
The ideal goal of Islamic law is to "protect human life" from harm and from evils. Genome modification is considered an "evil" by many because it alters the "prestige" and "dignity" of human beings.
However, another belief in Islam law is that "lesser evils are preferred over greater ones", so genome modification is often allowed because one may correct a major disease that will help generations to come
Fazli Dayan, Bangladesh Journal of Medical Science
"The technology is there. He [Jiankui] only did the experiment with the twin girls because he COULD and wanted to prove he could. It wasn't a developed an experiment, it wasn't thought about for consequences, he just wanted to be the FIRST. And why not? The technology is advanced, it's available, so he took the opportunity. And as research advances, laws may change, and TREATMENT may become legal in the coming decades for germline editing due to this availability."
Steve Dorus, PhD, Syracuse University