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DOSE-RESPONSE RELATIONSHIP NEEDS
BCA
CLASSIFICATION OF HEALTH EFFECTS
STEPS FORWARD
PROBLEMS RELATED TO BCA
BCA is a process by which we estimate the value of goods and services that will not be produced as a result of a regulation
WHAT IS WTP?
With the acronym WTP we refer to society's willingness to pay to reduce adverse health outcomes.
WTP FOR HEALTH IMPROVEMENTS INCLUDES VALUES OF:
avoided pain and suffering
1
2
CONSEQUENCES
2
1
Including health effects of disease other than cancer in BCA
The reduction in the possibility of developing diseases other than cancer is not quantified as one of the benefits
We get underestimated values
EPA (Environmental Protection Agency) use standard terms to express the degree of confidence in the association between the exposure polluttant and a health outcome
MODERATE DEGREE OF CONFIDENCE
HIGH DEGREE OF CONFIDENCE
"suggestive"
PROBLEMS IN CLASSIFICATION
"known"
"causal"
"likely"
EPA excludes it from BCA
but
WTP to reduce the risks is usually greater for more sever health effects with "suggestive" evidence rather than for less serious effects on health with a “known” evidence.
so
if the EPA does not quantify serious health effects with less certain evidence, we have underestimated WTP values.
1
2
EPA provides a reference dose (RfD) for health effects other than cancer
and
RfD is different for each person both for intrinsic factors and for acquired ones.
CONSEQUENCES
1
we cannot measure the risk of adverse outcomes for every level of exposure above or below the RfD.
2
If we considered a single reference dose, we would underestimate benefits
The NAS recommends not to assume a reference threshold, unless we consider a single category of people.
≠
including in BCA benefits from reducing noncancer health-effects
A presentation by:
Elena Biondi
Giovanni Sideri
Gianluigi Sponsillo