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She's born at Manchester in England.
She the world’s first baby to be conceived via in vitro fertilization (IVF)
Before giving birth to Louise, Lesley Brown had suffered years of infertility due to blocked fallopian tubes. In November 1977, she underwent the then-experimental IVF procedure.
The two men who pioneered the treatment - gynaecologist Patrick Steptoe and Nobel Prize-winning physiologist Robert Edwards - "had gone through hundreds of embryo transfers before Louise was conceived", he adds.
A special birth
Her birth attracted controversy, with religious leaders expressing concern about the use of artificial intervention and some raising fears that science was creating "Frankenbabies", but also paved the way for millions of women to undergo IVF.
Today, IVF is considered a mainstream medical treatment for infertility. Hundreds of thousands of children around the world have been conceived through the procedure, in some cases with donor eggs and sperm.