Huntington's
Disease
What is Huntington's disease
Huntington's disease is an aggressive brain order that causes you to lose control of your body and loss of thinking ability, and you know you are going to rage because you cant doing anything that you want to do. Its a tough life
Which Chromosome is Huntington's disease found on?
Is Huntington's Disease autosomal or sex linked?Dominant, Recessive, or Codominant?
Autosomal Dominant?
Huntington's disease is autosomal dominant.
Being autosomal dominant means that the offspring only has to inherit a single effected allele to get the disease
Huntington's disease is found on short arm of the fourth chromosome.
By: Jack Edwrads, Kayla Westmoreland, Dray Petree, Justin Kief
Symptoms of Huntington's Disease
Questions
1. What is Huntington's Disease?
2. What chromosome is it found on?
3. What are symptoms?
4. Is there a cure?
5. Is it dominant, recessive, or co-dominant?
Sources
- http://www.mayoclinic.org/diseases-conditions/huntingtons-disease/basics/definition/con-20030685
- http://www.hdsa.org/
- http://sites.bu.edu/ombs/2013/11/01/could-there-be-a-cure-for-huntingtons-disease/
- http://vanhornhuntingtonsdisease.weebly.com
Other names for Huntington's disease
Adult Onset this is the most common type of Huntington's disease. Symptoms usually begin when people are in their thirties or forties. First signs likely include:
• depression
• irritability
• hallucinations
• psychosis
• minor involuntary movements
• poor coordination
• difficulty understanding new information
• trouble making decisions
Huntington's disease stats
- hunnigoton chorea
- hunnigoton chronic proggresive heradity chorea
Symptoms of Huntington's Disease
This disorder is found in 3 to 1000000 people and less likely not to be found in chinese, and african descent.
Early Onset This type of Huntington's Disease is less common. Symptoms usually start to appear in early childhood or adolescence. Early-onset Huntington's disease causes mental, emotional, and physical changes, such as:
• drooling
• clumsiness
• slurred speech
• slow movements
• frequent falling
• rigid muscles
• seizures
• sudden decline in school performance
Diagnosis
The diagnosis depends on the persons symptoms of the disease, if the diseases symptoms are noticeable, then they will look into it to see if you have the disease.
Thank You!
Research?
Cure? Gene therapy?
Since 1999, there has been millions and millions of dollars spent on research for Huntington's Disease. In October 28, 2014, scientist in Florida, using a animal model of Huntington's Disease showed for the first time a functional connection between huntingtin and mTOR, a developmentally important gene that integrates signals from multiple pathways, such as growth factors and hormones, to regulate a variety of cell functions.
Treatment for gene defect? Treatable symptoms?
- There is no cure. The only thing you can do is lessen the symptoms.
- Researchers are looking into gene therapy but it would require brain surgery.
- There is nothing you can do once you get the gene.
- The symptoms are treatable by medicine which is prescribed by the symptoms.
- •Dopamine blockers may help reduce uncontrolled movements.
- •Drugs such as amantadine and tetrabenazine are used to try to control extra movements.
- Also different kinds of therapy helps.
Is Huntington's disease fatal?
Huntington's disease is a 100% fatal you can not function on your own and it eats at your brain. You could just choke on your own spit honestly.