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Metabolic Poisons
36
Oligomycin
Uncoupling Agents
Diagram of Uncoupling agent UCP
Diagrams of Oligomycin Inhibition and its afects
Oligomycin
Oligomycin
It binds to the proton channel of ATP Synthase, therefore preventing oxidative phosphorylation.
This is irreversible because ATP synthase can no longer move protons against the concentration gradient.
All uncoupling agents perform the same function but in different ways. See the wiki for more details.
Electron Transport Inhibitors
Diagram of DNP and its affects on respiration.
Video of Electron Transport Inhibitors. (Cyanide)
Uncoupling Agents
All uncoupling agents perform the same function but in different ways. See the wiki for more details.
Some of them are DNP and FCCP.
Electron Transport Inhibitors
Essential Questions
All electron inhibitors have the same function and some examples include: Rotenone, Antimycin, Cyanide, DNP, and Malonate.
They bind somewhere on the electron chain, preventing the passing of electrons.
This hinders the various metabolic processes.
What is a metabolic poison?
How do they affect cellular respiration?
Background Information
CELLULAR RESPIRATION
A metabolic poison directly interferes with a biochemical pathway involved in energy production or utilization.
The different types of metabolic poisons have different characteristics and act at different times during respiration, but all three types affect cellular respiration in the same way.
Types of Inhibitors
Metabolic Poisons