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Klinfelter Syndrome.

Randall Ceneus & Katie Walker

Interesting Factual Information

  • George Washington was reported to have Klinfelter's Syndrome.
  • Women conceiving over the age 35 increase the child's chance of having KLS.
  • A male with KLS has the same percentage chance of getting breast cancer as the general population of females.
  • KLS increase risks of Osteoporosis, Lung disease, ADHD, Dyslexia, and many other illnesses.

Normal Male

Male with Klinfelter's Syndrome

  • Abnormal body proportions
  • Abnormally large breasts (gynecomastia)
  • Infertility
  • Unusually small penis (micropenis)
  • Small, firm testes
  • Tall height
  • Less than normal amount of body hair
  • Decreased production of Testosterone

Symptoms:

This syndrome only affects the male sex chromosomes. A male normally has 46 chromosomes- one X and Y chromosome, but with KLS a male has at least one extra X chromosomes (XXY) in most of their cells.

TESTS:

Klinfelter"s sydrome is a chromosomal condition that affects male physical and cognitive development.

  • Karyotyping
  • Semen count
  • Blood Tests

The chromosomal changes occur as random events during the formation of reproductive cells in a parent. Nondisjunction causes the abnormal number of chromosomes. Though random, it occurs frighteningly often; it affects 1 out of every 500-700 males -making it the most common sex-chromosome abnormality.

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