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The gingiva appears red with a tendency to bleed
Patient presents with soreness of the oral cavity, which interferes with eating, drinking and oral hygiene
Epithelium
1- Balooning degeneration (acantholysis, nuclear clearing and enlargment)
2-Infected cells fuse to form multinucleated cells
3- Intercellular edema leads to formation of vesicles
4-Intranuclear inclusion bodies
The ruptured vesicles are focal sites of pain
Connective tissue
1- Acute Inflammatory infiltrate
2- Engorged blood vessels
1-Patient's history and clinical evaluation
2-HSV isolation by cell culture
3-Tzank smear
An infection of the oral cavity caused by herpes simplex virus type 1 (HSV-1)
1- Carranza's Clinical periodontology for south asia. 11th edition
2- Cawson's essential of oral pathology and oral medicine
SIGNS
Antiherpetic drug Acyclovir
Soft diet
Increased fluid intake
Bed rest
It is initially characterized by the presence of discrete, spherical, gray vesicles on the gingiva, mucosa and the tongue
1-Aphthous stomatitis
2-Necrotizing ulcerative gingivitis
3-Erythema multiforme
4-Stevens-jhonson syndrome