NICOTINE REPLACEMENT THERAPY
What is Nicotine Replacement Therapy?
PATCH
LOZENGE
- Medically-approved methods to receive nicotine other than through tobacco
- Used to help quit smoking cigarettes
- Contain small doses of nicotine to fight cravings
- Doses of nicotine are gradually decreased until no longer needed
- nicotine is passed through the skin into the bloodstream
- available over the counter
- gradually switch to lower-dose patches
- FDA approved to be used for 3-5 months
- available over the counter
- nicotine absorbed through mucous membranes of mouth
- (like nicotine gum) available in 2 strengths: 2 mg & 4 mg
- dose chosen depending on how long after waking up the individual has his/her first cigarette
Side Effects
Recommendations
Application
Side Effects
nausea
heart burn
hiccups
headache
gas
trouble sleeping
use for 12 weeks:
1 lozenge every 2 hrs for first 6 weeks
1 every 2-4 hrs for weeks 7-9
1 every 4-8 hrs for weeks 10-12
do not eat/drink 15 min before use
suck on lozenge until fully dissolved (~20-30 min)
do not bite, chew, or swallow
do not use > 5 in 6 hours, or > 20 per day
do not use with other NRTs
- applied on skin preferably in the morning
- apply onto clean, dry, non-hairy surface of skin, below neck & above waist
- different forms of patches:
- 16 hour patch: for light/average smokers
- 24 hour patch: for heavier smokers; helps with early morning withdrawal
Skin irritation
Racing heart beat
Sleeping problems/unusual dreams
Headache
Nausea
Muscle aches & stiffness
Choosing a NRT method
Types of Nicotine Replacement Therapy
- Depends on your lifestyle & pattern of smoking
- Gums, lozenges, & inhalers—allow user to control dosage of nicotine to aid in keeping cravings under control
- Nasal spray—works quickly & fights cravings in the moment
- Inhalers—mimic cigarettes (puffing & holding the inhaler)
- Patches—convenient; only need to be applied 1x a day
GUM
5 methods approved by the FDA:
1. Patch (transdermal nicotine systems)
2. Gum (nicotine polacrilex)
3. Nasal spray
4. Inhalers
5. Lozenges
- Fast-acting
- Nicotine absorbed thru mucous membranes of mouth
- available over the counter
- comes in 2 & 4 mg strengths
- do not eat ~15 min before or during use
- max. 24 pieces of gum per day
- recommended use: 6-12 weeks
- best to use on a fixed schedule during the day
INHALER
Side Effects
- requires prescription
- thin plastic tubes with a nicotine cartridge inside
- When taking puff from inhaler, the cartridge puts out a pure nicotine vapor
- Delivers most of nicotine vapor to the mouth– absorbed into bloodstream
- Recommended dose: 4-20 cartridges per day (slowly tapering off over 6 months)
bad taste
jaw discomfort
increased heart rate
throat irritation
nausea
hiccups
mouth sores
potential dentures/dental damage
Risks
Side Effects
- keep away from small children & pets--even used cartridges contain harmful amounts of nicotine
- most expensive NRT
mouth/throat irritation
coughing
stomach pains
NASAL SPRAY
References
- requires prescription
- send nicotine to bloodstream quickly
- quickly relieves withdrawal symptoms & allows for good control over cravings
- easy to use
- FDA recommends: use for 3-month periods & no longer than 6 months
Side Effects
Risks
- not recommended for people with allergies, asthma, nasal polyps, or sinus problems
- keep away from small children & pets--even empty bottles contain harmful amounts of nicotine
- if have any skin contact, immediately rinse with water
- if bottle breaks or liquid leaks, wear gloves to avoid direct contact
most common side effects last ~1-2 weeks
nasal irritation
runny nose
throat irritation
coughing
watery eyes
- http://www.determinedtoquit.com/howtoquit/methodsofquitting/nicotinereplacementtherapies/
- https://www.icanquit.com.au/quit-guide/methods-to-quit/nicotine-replacement-therapy/how-nicotine-replacement-therapy-works
- http://healthpsych.psy.vanderbilt.edu/health-patch.htm
- https://www.icanquit.com.au/quit-guide/methods-to-quit/nicotine-replacement-therapy/how-nicotine-replacement-therapy-works
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