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Uner Tan Syndrome
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Transcript
Uner Tan Syndrome
Predisposing Factors
Signs & Symptoms
- UTS is associated with intrafamilal marriages which suggest an autosomal recessive transmission
- There are no environment factors that forced the affected individuals to walk on all fours although some auhtors suggested the environment has a strong determining effect on quadrupedality
- May be related to the theory of human backward evolution or de-evolution which is the notion that species revert into more "primitive" forms over time.
Biological Changes
- Abnormalities to chromosomes 9p24
- A deformity of VLDLR is found on chromosome 9p24
What is UTS?
Habitual Quadrupedalism
- UTS is characterized by cerebellar hypoplasia
- loss of balance and coordination
- impaired cognitive abilities and habitual quadrupedal gait on hands and feet
- Is the the primary characteristic of Uner Tan Syndrome
- There are two types of quadrupedal locomotion:
- Diagonal sequence
- Lateral sequence
Types of UTS
- In diagonal sequence the foot touches the ground followed by the contralateral hand
- In lateral sequence the foot touches the ground followed by the ipsilateral hand.
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