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In the early 1800's Franz Gall introduced phrenology. Theory claimed that bumps on the skull revealed mental abilities and traits.
Axon= messages pass to other neurons, muscles or glands; exiting through terminal buttons
Axon's surface is selectively permeable,
picky about what it let's in!
Acting like a key, the neurotransmitter unlocks
small channels of receiving site allowing ions to enter
receiving neuron
http://learn.genetics.utah.edu/content/addiction/reward/neurontalk.html
agonists and antagonists act on the neurotransmitters
Agonists= any substance that mimics or has a similar effect to a neurotransmitter (excite;
transmitter, drugs, hormone)
Antagonists= any substance that inhibits the
effect of a neurotransmitter (inhibit; drugs, poisons)
ACh (acetycholine)= enables muscle action, learning and memory
* lack of ACh associated with Alzheimer's
Dopamine= movement, learning, attention and emotion
* lack of can lead to Parkinson's
* excess associated with schizophrenia
Serotonin= mood, hunger, sleep, arousal
* lack of can lead to depression
Dendrite= bushy fibers that receive information
Reuptake= when excess neurotransmitters are reabsorbed by sending neuron
"AXONS SPEAK. DENDRITES LISTEN."
Myelin sheath= insulates axons; helps speed up impulses
Neurons process and transmit information throughout our body.
Excitatory neurotransmitters=
bring the dendrite closer to threshold by allowing positive ions to rush in.
* increase in positive charge in cell = excitatory!
more likely to fire action potential
Inhibitory neurotransmitters=
take the dendrite further away from threshold by allowing negative ions to rush in
* decrease in positive charge=more negative= inhibitory!
Evidence shows that people who suffer from multiple sclerosis do not have adequate insulation from the myelin sheath. As the sheath degenerates, the communication between neurons, muscles and glands slows. Can lead to sensory impairments, coordination difficulties and control of bodily functions.
synapse= the junction between axon end of sending neuron and dendrite or cell body of receiving neuron
synaptic gap/cleft= space between sending and receiving neuron
neurotransmitters= chemical messengers; released by sending neuron, travels across synapse and bind to receptor sites of receiving neuron (stored in vesicles)
Along the neuron= electrical; this is called an action potential
A neural, ELECTRICALLY CHARGED impulse that travels down the axon.
Between two neurons= chemical; this is called synaptic transmission
* fluid interior of a resting axon has negatively charged ions
* fluid outside axon membrane has positively charged ions
= Resting potential
Neural Communication Checklist
Depolarization= neuron fires from stimulation, gates open, positively charged sodium ions rush in
causes domino effect, further action potential along the axon
Resting Potential
* Charge
*Ions
Change in Charge
*Neurotransmitters
*Ions
*Failed attempt
*Reaching threshold (all-or-none)
threshold= level of stimulation required to trigger neural impulse
Refractory period= neuron pumps positive ions back out
a net flow of sodium ions into the cell causes rapid change in potential across the membrane
Neural Communication Checklist
Action Potential
*Firing
*Ions
*Myelin
*Depolarization
Refractory Period
* Sodium gates close, potassium pumped out
*negative charge restored
* back to resting potential
Neurons either fire or they don't;
it is an all-or-none response!