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Transcript

DNA Structure

Chemical Properties

  • Alternating Backbone
  • Phosphate and Sugar Group
  • 4 Nitrogenous Bases
  • thymine-adenine(2 hydrogen bonds)
  • guanine-cytosine(3 hydrogen bonds)
  • Bonds
  • Phosphodiester, hydrogen, and glycosyl Bonds
  • Anti-Parallel
  • 5' and 3' ends

DNA Replication

Initiation

  • Semi-conservation
  • Parent and Daughter Strand
  • Origins of Replication
  • Replication Fork and Bubble
  • Enzymes
  • DNA Helicase
  • DNA Gyrase
  • Single Stranded Binding Proteins(SSBs)
  • Anneal and Re-anneal

Lagging Strand

Leading Stand

  • Continuously synthsized
  • One RNA Primer
  • Towards Replication Fork in the 5'to 3 prime direction
  • Discontinuously Synthesized
  • Many RNA primers
  • Away from Replication Fork in the 3'to 5'direction
  • DNA Polymerase 3
  • DNA Polymerase 1
  • DNA Ligase
  • Okazaki Fragments

Physical Properties

The diameter of DNA is 2nm

DNA Structure and Replication

  • The helix makes one complete turn every 10 nucleotides.
  • The distance between nucleotides is 0.34nm
  • One complete turn accounts for 3.4nm

DNA Structure

DNA stands for DeoxyriboNucleic Acid

and its in the shape of a double helix

Emma Ratia

Termination

  • DNA polymerase 1 and 3
  • Proofreading
  • Mistakes
  • Exonuclease

March 11th 2015

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