Introducing 

Prezi AI.

Your new presentation assistant.

Refine, enhance, and tailor your content, source relevant images, and edit visuals quicker than ever before.

Loading…
Transcript

Cause

Treatments

-You need two genes to make enough beta globin protein chains

-If one or both of these genes are altered, you'll have beta thalassemia

  • one altered gene = carrier w/ mild anemia
  • two altered genes = major anemia or Cooley's
  • Regular blood transfusions
  • Transfusions can cause iron to build up in the blood (damage heart and liver)
  • iron chelation therapy to remove excess iron from the body
  • Folic acid is a B vitamin that helps build healthy red blood cells
  • stem cell transplant is the only treatment that can cure thalassemia

Prognosis

  • can cause early death due to heart failure, usually between ages 20 and 30
  • regular blood transfusions and therapy to remove iron from the body helps improve the outcome

  • Genetic counseling and prenatal screening may help people with a family history of this condition who are planning to have children.

Special Care

after transfusions and other surgical methods are used, patients are usually given antibiotics after obtaining regular urine samples

Cooley's Anemia

Karyotype

The beta globin gene is located on chromosome 11. A child inherits two beta globin genes (one from each parent)

inherited by an autosomal recessive gene

tests:

complete blood count

hemoglobin electrophoresis

Physical Manifestations

  • usually seen in first two years of life
  • poor appetite
  • jaundice
  • dark urine
  • slow growth/ delayed puberty
  • enlarge spleen, liver, or heart
  • bone problems (mostly face)

Sources

complete lack of beta protein in the hemoglobin causes a life-threatening anemia that requires regular blood transfusions and extensive ongoing medical care

  • http://www.thalassemia.org/learn-about-thalassemia/about-thalassemia/
  • http://www.nhlbi.nih.gov/health/health-topics/topics/thalassemia/prevention.html
  • http://www.nlm.nih.gov/medlineplus/ency/article/000587.htm

Learn more about creating dynamic, engaging presentations with Prezi