Nanotechnology in Cosmetics

To obtain REAL consumer perceivable benefits and optimize sensory attributes, formulators are resorting to high tech. delivery systems used in pharmaceutical products

In cosmetics, the main concern is to reach cutaneous cell while limiting passage into blood

Consumer Demand

Multifunctional products with focus on treatment and aesthetics

Scientist Formulates

Electrospinning:

A. Coaxial needle:

provides feeding of two different polymers or encapsulation of agents, drugs and other bioactives insid the shell polymer acting as carrier

Applications:

Nanofibers are designed by choosing suitable polymers, convenient additives, and proper synthesis, which includes:

• Self-assembly
• drawing
• meltblowing
• template synthesis
• phase separation
• melt spinning
• centrifugal spinning
• electrospinning

facial masks and skin cleansings, skin health and renewal products, skin wound dressings and drug delivery products

The rate of feeding, electric field force acting on polymer solution/melt, and flight distance of poymer jet are key parameters

Principle of Electrospinning:

1. charging of polymer solution/melt causing a deformation on the droplet at the tip and formation of cone

2. generation of jet by increasing charging

3. elongation of jet

4. deformation of straight jet segment, creation of instability, and continuation of elongation

5. solidification of nanofibers by evaporation of solvent or cooling

6. collecting fibers on collector

B. Rotating drum collector:

They develop the fiber structure, provide molecular arientation and make electrospinning easy with high angular velocity

High S.A/V leads to enhanced liquid absorption capacities and increased rentention levels of actives as well as high contact surface between nanofibers and skin provides delivery of cosmetic agents to the deeper skin parts.

Cosmetic Delivery Systems:

and finally, Nanofibers..

forming the broadest class of nanomaterials due to their unique properties, such as high surface-area-to-volume ratios, low diameters, high porosity, high strength, low basis weight, and small pore sizes making them excellent candidates for delivery

The objective of topical therapy:

1. Vesicular Systems

• liposomes
• silicone vesicles and matrices
• multi-walled delivery systems

2. Emulsions

• microemulsions
• liquid crystals
• multiple emulsions
• nanoemulsions
• pickering emulsions

3. Particulate Systems

• microparticulates
• porous polymeric systems
• nanoparticulates
• cyclodextrin complexes

1. To modulate or assist the barrier function of skin (i.e TEWL, leaching of moisturizing factors, etc)

2. To administer an active ingredient to one or more skin layers or compartments while minimizning systemic

In the aim of delivering one or more of the below five effects:

skin cleansing, decoration, care, hydration or protection

nano-sized structures show great potential due their unique intrinsic properties arising from their small size. They do not clog skin pores and allow penetration of air and water soluble materials, while many types of cosmetics cause accumulation of oil layer on the skin and block passing of air, water, vitamin, etc, through skin.

Nanotechnology in Cosmetics

By: Sham AlZahabi