Introduzione
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After four weeks of the "lung" being in the nutritious liquid it is taken out as a, "just pinker, softer and less dense" version of a lung. Then finally the researchers reseed the lab-grown lungs with cells.
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How?
Naturally pigs have similar sized organs as humans and share the same uses for them. This makes it so when the pig grows the human organs it will not effect its health state. The first step to this is to edit a pigs embryo deleting the DNA that allowed it to grow a pancreas. After this a human stem cell is inserted into the embryo filling the gap allowing the pig to grow an human pancreas.
Cross-species
Over the last couple of year US scientist have been trying to build human organs inside of pigs.
Relation to Genetics
This technique of growing artificial lungs is related to genetics because of its use of gene therapy. To build the pancreas it altered a pigs gene similar
Final Steps
Once the embryo has the human stem cells it is implanted into a sow and allowed to develop for 28 days. It is hoped that then this pig will grow a human pancreas. This technique is also currently being tested for other human organs too.
Using the skeleton of the lung as scaffolding the researchers harvested stem cells from the other lung and applied them onto the scaffolding. After this the "lung" is placed into a chamber filled with nutritious liquid for four weeks.
Relation to genetics
Unlike the organs currently found in your bodies, these special organ are grown in scientific lab using stem cells or are made in genetically altered animals. Artificial organs is one of the main tools being used to fight against the worlds need for more organs.
In recent experiments done by UTMB the first artificial lung has finally been produced. The first step that scientist did at UTMB was find the lungs of 2 children who died from trauma. With these lungs the researchers stripped down the lungs to their main skeleton of collagen and elastin.
The creation of artificial lungs relate to genetics because of the use of stem cells. This cell has the ability to make itself what ever it wants or is manipulated to be. Using genetic manipulation on the cells it is possible to build lung cells. After cells multiply it creates a tissue. Then the tissues grow to make an organ.
Stem cells are important because they have the remarkable potential to turn into different types of cells in the body during early life and growth. Stem cells can also work as an repair system because whenever a stem cell splits they new cells can either turn into another stem cell or whatever the organ needs.
Tissue Engineering
This new field in biomedical engineering throws cell biologist, surgeons, and engineers onto one team. An enormous demand for tissue and organ transplants worldwide are making companies search for new and creative ways to complete this demand. Tissue engineering is what many companies have came up with to fill this demand. Tissue engineering is the use of a combination of cells, biochemicals, and physicochemical to improve or make tissue.