Introducing
Your new presentation assistant.
Refine, enhance, and tailor your content, source relevant images, and edit visuals quicker than ever before.
Trending searches
*Continued transfusion of blood from the placenta to the newborn
*Higher hemoglobin concentrations
*Increased iron stores/Ferritin levels
*Decreased incidences of iron deficiency anemia
*Decreased side effects that result from anemia
PICO Question:
In term newborns, does delayed cord clamping decrease anemia and increase iron stores as compared to immediate clamping of the cord after birth?
While some findings showed that delayed cord clamping can cause slight increases in bilirubin levels, the positive effects of delayed cord clamping out weigh the negative. Anemia is a serious condition in infants but delayed cord clamping may decrease the long-term side effects of anemia.
Andersson, O., Hellstrom-Westas, L., Andersson D., Domellof, M. (2011) Effect of delayed versus early umbilical cord clamping on neonatal outcome and iron status at 4 months: a randomized controlled trial. http://www.bmj.com/content/343/bmj.d7157
KC, A., Malqvist, M., Rana N., Ranneberg, L. J., Andersson, O., (2014) Effect of timing of umbilical cord clamping on anaemia at 8 and 12 months and later neurodevelopment in late pre-term and term infants; a facility-based, randomized-controlled trial in Nepal. https://bmcpediatr.biomedcentral.com/articles/10.1186/s12887-016-0576-z
Hutton, E. K., Hassen, E. S., (2007) Late vs early clamping of the umbilical cord in full-term neonates: systematic review and meta-analysis of controlled trials. https://www.ncbi.nlm.nih.gov/pubmed/17374818?dopt=abstract
Level II, randomized control trial
*400 full term infants, Swedish County Hospital
*Interventions: delayed cord clamping for 3 minutes, early clamping within 10 seconds of birth
*Results: delayed cord clamping-fewer incidences of iron deficiency anemia, average of 96g higher weight, less blood retained in the placenta, increased iron stores
Level II, randomized control trial:
*Performed at the Paropakar Maternity and Women's Hospital in Kathmandu, Nepal.
*One group: delayed cord clamping until 3 minutes after birth
*Second group: early clamping of less than 60 seconds
*Results: delayed cord clamping group-increased placental transfusion, fewer incidences of infant anemia, greater iron stores
Level I, meta-analysis review
*Reviewed 15 controlled trials using 1,912 newborns: 1,001 cords clamped 2 minutes after birth, 911 cords clamped immediately
*Results: delayed cord clamping group- increased hematocrit levels, increased ferritin concentrations, reduction of iron deficiency anemia