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Cleft lip (cheiloschisis) and cleft palate (palatoschisis),
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The development of the face is coordinated by complex morphogenetic events and rapid proliferative expansion, and is thus highly susceptible to environmental and genetic factors, rationalising the high incidence of facial malformations. During the first six to eight weeks of pregnancy, the shape of the embryo's head is formed. Five primitive tissue lobes grow
Cleft lip and Cleft palate are not only human but also can happen animals but rarely sheep,cats,dogs,and horses
a) one from the top of the head down towards the future upper lip; (Frontonasal Prominence) b-c) two from the cheeks, which meet the first lobe to form the upper lip; (Maxillar Prominence) d-e) and just below, two additional lobes grow from each side, which form the chin and lower lip; (Mandibular Prominence)
If these tissues fail to meet, a gap appears where the tissues should have joined (fused). This may happen in any single joining site, or simultaneously in several or all of them. The resulting birth defect reflects the locations and severity of individual fusion failures (e.g., from a small lip or palate fissure up to a completely malformed face).
Approximately 1 in 700 children born have a cleft lip or a cleft palate or both. Clefts can also affect other parts of the face, such as the eyes, ears, nose, cheeks, and forehead
Cleft lip (cheiloschisis) and cleft palate (palatoschisis), which can also occur together as cleft lip and palate, are variations of a type of clefting congenital deformity caused by abnormal facial development during gestation
Gestation-The process of being carried in the womb betweeen conception and birth or the development of something over a period of time.