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Muscimol Effects and Side Effects
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Transcript
Muscimol Effects and Side Effects
Case study
- Emily's friends ate mushrooms
- After 30 minutes they began salivating, perspirating heavily they began to have stomach cramps, vomiting and diarrhea, trouble breathing, this lasted for 2 hours
- Hallucination and drunken behavior which lasted for 4 hours
- They then recovered quickly
- They identify the mushroom as fly agaric known as Amanita muscaria.
Side Effects
Dont eat it!!
- Hallucinations
- muscular jerking
- Drowsiness
- Salivating
- Nausea
- Stomach cramps
- Many more
Pharmacology
What is Muscimol?
- structurally similar to GABA
- GABAA Agonist
- Alters neural activity in multiple regions
- Causes for an inhibitory effect
- Psychoactive constituent of Amanitia muscaria
- produced naturally in mushroom
- effects of intoxication
- found in layer below the skin
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